Antineoplastic agents 157. Quassia kerstingII1

George Pettit, S. B. Singh, A. Goswami, R. A. Nieman

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

The oxacanthin alkaloid components of Quassia kerstingü L. have been found to be 2-hydroxy- and ll-hydroxy-canthin-6-one (1a and 1b). Structure 1a was confirmed by results of methylation (1a → 1c + 2a) and NOE studies. A selective INEPT NMR technique was employed to support unequivocally the 11-hydroxy-canthin-6-one (1b) assignment.

Original languageEnglish (US)
Pages (from-to)3349-3354
Number of pages6
JournalTetrahedron
Volume44
Issue number11
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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    Pettit, G., Singh, S. B., Goswami, A., & Nieman, R. A. (1988). Antineoplastic agents 157. Quassia kerstingII1. Tetrahedron, 44(11), 3349-3354. https://doi.org/10.1016/S0040-4020(01)85969-X