Antineoplastic agents, 118. isolation and structure of bryostatin 9

George Pettit, Yoshiaki Kamano, Cherry L. Herald

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Marine Bryozoa in the Bugulidae family are generally very efficient at establishing new colonies (usually flexible) that may reach 5 cm in length. Part of this success has been attributed to the snapping beak (avicularia) protecting each zooid (2). While well known for its colonizing success, Bugula neritina L., unlike other closely related Bugula species, does not have avicularia. Results of our chemical investigation of this fascinating animal suggest that its notable survival abilities may reside in extraordinary chemical rather than physical defenses.

Original languageEnglish (US)
Pages (from-to)661-664
Number of pages4
JournalJournal of Natural Products
Volume49
Issue number4
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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