Antigen Delivery System II: Development of Live Attenuated Bacterial Vectors

Roy Curtiss

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Abstract

This chapter reviews papers mostly written since 2005 that report results using live attenuated bacterial vectors to deliver after administration through mucosal surfaces, protective antigens, and DNA vaccines, encoding protective antigens to induce immune responses and/or protective immunity to pathogens that colonize on or invade through mucosal surfaces. Papers that report use of such vaccine vector systems for parenteral vaccination or to deal with nonmucosal pathogens or do not address induction of mucosal antibody and/or cellular immune responses are not reviewed.

Original languageEnglish (US)
Title of host publicationMucosal Immunology: Fourth Edition
PublisherElsevier Inc.
Pages1233-1269
Number of pages37
Volume1-2
ISBN (Print)9780124159754, 9780124158474
DOIs
StatePublished - Apr 1 2015

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Keywords

  • Antigen delivery
  • Attenuation
  • DNA vaccine
  • Lactobacillus
  • Mucosal associated lymphoid tissue (MALT)
  • Mucosal immunity
  • Mutation
  • Plasmid
  • Salmonella
  • Sublingual immunization

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

Cite this

Curtiss, R. (2015). Antigen Delivery System II: Development of Live Attenuated Bacterial Vectors. In Mucosal Immunology: Fourth Edition (Vol. 1-2, pp. 1233-1269). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-415847-4.00064-1