Antifungal activity and mechanism of monocaprin against food spoilage fungi

Maomao Ma, Xuefang Wen, Yuting Xie, Zhen Guo, Rongbin Zhao, Ping Yu, Deming Gong, Shuguang Deng, Zheling Zeng

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Monocaprin is generally recognized as a safe food additive and widely used as a functional emulsifier in food industry. In this work, the preservative ability of monocaprin against three food spoilage fungi, Saccharomyces cerevisiae, Aspergillus niger and Penicillium citrinum was investigated to evaluate the potential use of monocaprin as a potent food preservative. The minimum inhibitory concentrations (MIC) of monocaprin against these fungi were 0.31, 0.63 and 0.63 mg/mL, and the minimum fungicidal concentrations were 1.25, 2.50 and 2.50 mg/mL, respectively. The MICs remained unchanged when the pH values were increased from 3 to 9. After being exposed to monocaprin at MIC, the growth of A. niger or P. citrinum was completely inhibited for one week, and S. cerevisiae began to degrade at 100 h. These results indicated that monocaprin may be a potential preservative independent of pH. The mechanism of action was then investigated by the measurement of damage of cell walls, permeability of cell membrane, release of cellular contents and morphological observation. Results indicated that monocaprin may kill S. cerevisiae by disrupting the cell wall and plasma membrane, resulting in the release of cellular contents. Monocaprin inhibited A. niger spore and P. citrinum by increasing the permeability of the cell membrane and release of cellular contents, but not involving cell structure alteration.

Original languageEnglish (US)
Pages (from-to)561-568
Number of pages8
JournalFood Control
Volume84
DOIs
StatePublished - Feb 1 2018

Fingerprint

Penicillium citrinum
food spoilage
Aspergillus niger
Saccharomyces cerevisiae
Fungi
membrane permeability
minimum inhibitory concentration
preservatives
Food
fungi
cell walls
food preservatives
cell structures
emulsifiers
food additives
Cell Membrane Permeability
food industry
mechanism of action
Microbial Sensitivity Tests
plasma membrane

Keywords

  • Food preservative
  • Food spoilage fungi
  • Mechanism of action
  • Monocaprin

ASJC Scopus subject areas

  • Biotechnology
  • Food Science

Cite this

Ma, M., Wen, X., Xie, Y., Guo, Z., Zhao, R., Yu, P., ... Zeng, Z. (2018). Antifungal activity and mechanism of monocaprin against food spoilage fungi. Food Control, 84, 561-568. https://doi.org/10.1016/j.foodcont.2017.07.022

Antifungal activity and mechanism of monocaprin against food spoilage fungi. / Ma, Maomao; Wen, Xuefang; Xie, Yuting; Guo, Zhen; Zhao, Rongbin; Yu, Ping; Gong, Deming; Deng, Shuguang; Zeng, Zheling.

In: Food Control, Vol. 84, 01.02.2018, p. 561-568.

Research output: Contribution to journalArticle

Ma, M, Wen, X, Xie, Y, Guo, Z, Zhao, R, Yu, P, Gong, D, Deng, S & Zeng, Z 2018, 'Antifungal activity and mechanism of monocaprin against food spoilage fungi', Food Control, vol. 84, pp. 561-568. https://doi.org/10.1016/j.foodcont.2017.07.022
Ma, Maomao ; Wen, Xuefang ; Xie, Yuting ; Guo, Zhen ; Zhao, Rongbin ; Yu, Ping ; Gong, Deming ; Deng, Shuguang ; Zeng, Zheling. / Antifungal activity and mechanism of monocaprin against food spoilage fungi. In: Food Control. 2018 ; Vol. 84. pp. 561-568.
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