Antibiotic and pesticide susceptibility and the Anthropocene operating space

Living with Resistance project

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Rising levels of antimicrobial and pesticide resistance increasingly undermine human health and systems for biomass production, and emphasize the sustainability challenge of preserving organisms susceptible to these biocides. In this Review, we introduce key concepts and examine dynamics of biocide susceptibility that must be governed to address this challenge. We focus on the impact of biocides on the capacity of susceptible organisms to prevent spread of resistance, and we then review how biocide use affects a broader suite of ecosystem services. Finally, we introduce and assess the state of what we term the Anthropocene operating space of biocide susceptibility, a framework for assessing the potential of antibiotic and pesticide resistance to undermine key functions of human society. Based on current trends in antibiotic, insecticide and herbicide resistance, we conclude that the states of all six assessed variables are beyond safe zones, with three variables surpassed regionally or globally.

Original languageEnglish (US)
Pages (from-to)632-641
Number of pages10
JournalNature Sustainability
Volume1
Issue number11
DOIs
StatePublished - Nov 1 2018

Fingerprint

Biocides
biocides
Disinfectants
Antibiotics
Pesticides
antibiotics
pesticides
pesticide
Anti-Bacterial Agents
pesticide resistance
antibiotic resistance
Microbial Drug Resistance
Herbicide Resistance
Insecticide Resistance
Insecticides
herbicide resistance
Herbicides
insecticide resistance
organisms
ecosystem service

ASJC Scopus subject areas

  • Ecology
  • Global and Planetary Change
  • Management, Monitoring, Policy and Law
  • Nature and Landscape Conservation
  • Geography, Planning and Development
  • Urban Studies
  • Renewable Energy, Sustainability and the Environment
  • Food Science

Cite this

Antibiotic and pesticide susceptibility and the Anthropocene operating space. / Living with Resistance project.

In: Nature Sustainability, Vol. 1, No. 11, 01.11.2018, p. 632-641.

Research output: Contribution to journalReview article

Living with Resistance project. / Antibiotic and pesticide susceptibility and the Anthropocene operating space. In: Nature Sustainability. 2018 ; Vol. 1, No. 11. pp. 632-641.
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