Anthracylmethyl crown ethers as fluorescence sensors of saxitoxin

Robert E. Gawley, Qianhui Zhang, Paul I. Higgs, Shaopeng Wang, Roger M. Leblanc

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Anthracylmethyl crowns 1 and 2 show up to 30-fold increase in fluorescence emission intensity in the presence of saxitoxin in ethanol, and sixfold enhancement in 80% ethanol. The binding constant between saxitoxin and 1 is 3880 M-1 in ethanol and 1100 M-1 in 80% ethanol.

Original languageEnglish (US)
Pages (from-to)5461-5465
Number of pages5
JournalTetrahedron Letters
Volume40
Issue number30
DOIs
Publication statusPublished - 1999
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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