To the Editor: Antacids continue to be the mainstay of medical management of acid peptic disorders. Though clinical experience suggests that antacids relieve ulcer pain, there are no experimental data demonstrating that antacids are more effective than placebo in relieving the pain of duodenal or gastric ulcer, that antacids speed healing of gastric or duodenal ulcer or that they prevent ulcer complications or recurrences.1 2 3 4 Clinicians have a bewildering array of antacids to choose from. The 1976 Physicians’ Desk Reference lists 36 antacids. A rational choice of antacids should be based on knowledge of the buffering effect, specific constituents of. No extract is available for articles shorter than 400 words.
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