TY - JOUR
T1 - Analysis of population genetic structure by DNA fingerprinting.
AU - Lynch, M.
N1 - Copyright:
This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 1991
Y1 - 1991
N2 - DNA fingerprint similarity is now being used widely to make inferences about the genetic structure of natural and domesticated populations, often with little regard to the limitations of such data. This paper provides an overview of the statistical theory of DNA fingerprint analysis with special focus on applications to natural populations for which little if anything is known about the detailed genetics of the DNA profiles. Approaches to estimating individual and population homozygosity, effective population size, population subdivision, and relatedness are reviewed, and issues concerning the biases and sampling properties of the statistics are discussed.
AB - DNA fingerprint similarity is now being used widely to make inferences about the genetic structure of natural and domesticated populations, often with little regard to the limitations of such data. This paper provides an overview of the statistical theory of DNA fingerprint analysis with special focus on applications to natural populations for which little if anything is known about the detailed genetics of the DNA profiles. Approaches to estimating individual and population homozygosity, effective population size, population subdivision, and relatedness are reviewed, and issues concerning the biases and sampling properties of the statistics are discussed.
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U2 - 10.1007/978-3-0348-7312-3_9
DO - 10.1007/978-3-0348-7312-3_9
M3 - Review article
C2 - 1831155
AN - SCOPUS:0025940964
VL - 58
SP - 113
EP - 126
JO - Experientia. Supplementum
JF - Experientia. Supplementum
SN - 1023-294X
ER -