Analysis of neuronal interactions during adaptation and learning in motor control of primates. A model independent approach using information theory

Narayanan Krishnamurthi, D. J. Weber, Jiping He, A. Prasad, L. D. Iasemidis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

In this study, we investigate how neurons from different cortices of the brain interact with each other during learning of a task, and how they adapt after perturbation in rhesus monkeys. The level of interaction between neurons over time was estimated through a nonparametric approach by calculating the mutual information between their neural spike trains. It was observed that the average mutual information between neurons was increased significantly within the motor cortex and between the motor and sensory cortices of the brain during the last days of the experiment. Moreover, the increased interactions within the motor cortex were observed before the onset of expected perturbations of arm movements, indicating that the neurons interact well in advance in anticipation of a perturbation, and coordinate their activity to adapt to the task faster and more successfully.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages2552-2553
Number of pages2
Volume3
StatePublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Other

OtherProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
CountryUnited States
CityHouston, TX
Period10/23/0210/26/02

Fingerprint

Information theory
Neurons
Brain
Primates
Experiments

Keywords

  • Adaptation
  • Learning
  • Motor control
  • Mutual information
  • Neural spike trains

ASJC Scopus subject areas

  • Bioengineering

Cite this

Krishnamurthi, N., Weber, D. J., He, J., Prasad, A., & Iasemidis, L. D. (2002). Analysis of neuronal interactions during adaptation and learning in motor control of primates. A model independent approach using information theory. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 3, pp. 2552-2553)

Analysis of neuronal interactions during adaptation and learning in motor control of primates. A model independent approach using information theory. / Krishnamurthi, Narayanan; Weber, D. J.; He, Jiping; Prasad, A.; Iasemidis, L. D.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. p. 2552-2553.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Krishnamurthi, N, Weber, DJ, He, J, Prasad, A & Iasemidis, LD 2002, Analysis of neuronal interactions during adaptation and learning in motor control of primates. A model independent approach using information theory. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 3, pp. 2552-2553, Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS), Houston, TX, United States, 10/23/02.
Krishnamurthi N, Weber DJ, He J, Prasad A, Iasemidis LD. Analysis of neuronal interactions during adaptation and learning in motor control of primates. A model independent approach using information theory. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3. 2002. p. 2552-2553
Krishnamurthi, Narayanan ; Weber, D. J. ; He, Jiping ; Prasad, A. ; Iasemidis, L. D. / Analysis of neuronal interactions during adaptation and learning in motor control of primates. A model independent approach using information theory. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 3 2002. pp. 2552-2553
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