Analysis of field-effect biosensors using self-consistent 3d drift-diffusion and Monte-Carlo simulations

S. Baumgartner, M. Vasicek, A. Bulyha, N. Tassotti, C. Heitzinger

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Field-effect biosensors based on nanowires enjoy considerable popularity due to their high sensitivity and direct electrical readout [1]. However, crucial issues such as the influence of the biomolecules on the charge-carrier transport or the binding of molecules to the surface have not been described satisfactorily yet in a quantitative manner. In order to analyze these effects, we present simulation results based on a 3D macroscopic transport model coupled with Monte-Carlo simulations for the bio-functionalized surface layer. Excellent agreement with measurement data has been found, while detailed study of the influence of the most prominent biomolecules, namely double-stranded DNA and single-stranded DNA, on the current through the semiconductor transducer has been carried out.

Original languageEnglish (US)
Title of host publicationProcedia Engineering
Pages407-410
Number of pages4
Volume25
DOIs
StatePublished - 2011
Externally publishedYes
Event25th Eurosensors Conference - Athens, Greece
Duration: Sep 4 2011Sep 7 2011

Other

Other25th Eurosensors Conference
CountryGreece
CityAthens
Period9/4/119/7/11

Keywords

  • Field-effect biosensors
  • Field-effect DNA sensors
  • Sensor simulation
  • Silicon nanowire

ASJC Scopus subject areas

  • Engineering(all)

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    Baumgartner, S., Vasicek, M., Bulyha, A., Tassotti, N., & Heitzinger, C. (2011). Analysis of field-effect biosensors using self-consistent 3d drift-diffusion and Monte-Carlo simulations. In Procedia Engineering (Vol. 25, pp. 407-410) https://doi.org/10.1016/j.proeng.2011.12.101