An international database and integrated analysis tools for the study of cancer gene expression

R. L. Strausberg, A. A. Camargo, G. J. Riggins, C. F. Schaefer, S. J. De Souza, L. H. Grouse, A. Lal, K. H. Buetow, K. Boon, S. F. Greenhut, A. J.G. Simpson

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Researchers working collaboratively in Brazil and the United States have assembled an International Database of Cancer Gene Expression. Several strategies have been employed to generate gene expression data including expressed sequence tags (ESTs), serial analysis of gene expression (SAGE), and open reading-frame expressed sequence tags (ORESTES). The database contains six million gene tags that reflect the gene expression profiles in a wide variety of cancerous tissues and their normal counterparts. All sequences are deposited in the public databases, GenBank and SAGEmap. A suite of informatics tools was designed to facilitate in silico analysis of the gene expression datasets and are available through the NCI Cancer Genome Anatomy Project web site (http://cgap.nci.nih.gov).

Original languageEnglish (US)
Pages (from-to)156-164
Number of pages9
JournalPharmacogenomics Journal
Volume2
Issue number3
DOIs
StatePublished - 2002

Keywords

  • CGAP
  • Cancer
  • Gene expression
  • Genomics
  • ORESTES
  • SAGE

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Pharmacology

Fingerprint Dive into the research topics of 'An international database and integrated analysis tools for the study of cancer gene expression'. Together they form a unique fingerprint.

Cite this