Airborne nanostructured particles and occupational health

Andrew Maynard, Eileen D. Kuempel

Research output: Contribution to journalArticle

409 Citations (Scopus)

Abstract

Nanotechnology is leading to the development in many field, of new materials and devices in many fields that demonstrate nanostructure-dependent properties. However, concern has been expressed that these same properties may present unique challenges to addressing potential health impact. Airborne particles associated with engineered nanomaterials are of particular concern, as they can readily enter the body through inhalation. Research into the potential occupational health risks associated with inhaling engineered nanostructured particles is just beginning. However, there is a large body of data on occupational and environmental aerosols, which is applicable to developing an initial assessment of potential risk and risk reduction strategies. Epidemiological and pathological studies of occupational and environmental exposures to airborne particles and fibers provide information on the aerosol-related lung diseases and conditions that have been observed in humans. Toxicological studies provide information on the specific disease mechanisms, dose-response relationships, and the particle characteristics that influence toxicity, including the size, surface area, chemistry or reactivity, solubility, and shape. Potential health risk will depend on the magnitude and nature of exposures to airborne nanostructured particles, and on the release, dispersion, transformation and control of materials in the workplace. Aerosol control methods have not been well-characterized for nanometer diameter particles, although theory and limited experimental data indicate that conventional ventilation, engineering control and filtration approaches should be applicable in many situations. Current information supports the development of preliminary guiding principles on working with engineered nanomaterials. However critical research questions remain to be answered before the potential health risk of airborne nanostructured particles in the workplace can be fully addressed.

Original languageEnglish (US)
Pages (from-to)587-614
Number of pages28
JournalJournal of Nanoparticle Research
Volume7
Issue number6
DOIs
StatePublished - Dec 2005
Externally publishedYes

Fingerprint

Occupational Health
Health risks
Aerosols
health
Health
Nanostructured materials
Occupational risks
Aerosol
aerosols
Pulmonary diseases
Nanomaterials
Nanotechnology
Particles (particulate matter)
Ventilation
Toxicity
Nanostructures
Solubility
particle theory
Fibers
ventilation

Keywords

  • Aerosol
  • Environment
  • Exposure
  • Exposure control
  • Exposure measurement
  • Health
  • Inhalation
  • Nanoparticle
  • Nanostructured particle
  • Nanotechnology
  • Risk
  • Ultrafine

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Engineering (miscellaneous)
  • Materials Science (miscellaneous)

Cite this

Airborne nanostructured particles and occupational health. / Maynard, Andrew; Kuempel, Eileen D.

In: Journal of Nanoparticle Research, Vol. 7, No. 6, 12.2005, p. 587-614.

Research output: Contribution to journalArticle

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