Fibrinogen is found to be able to produce highly molecular aggregates in solution. Its maximal quantity aggregates at the temperature of 4 degrees C. The pH dependence of fibrinogen aggregates production is shown. Highly molecular aggregates of fibrinogen are found to be produced mainly due to hydrogen bonds. Electron-microphotography of aggregated fibrinogen is presented. Complementary molecular loci responsible for the formation of ordered aggregates are discussed from the standpoint of their significance in the fibrin polymerization.
|Translated title of the contribution||Aggregation of fibrinogen molecules in a solution|
|Number of pages||9|
|Journal||Ukrainskii biokhimicheskii zhurnal|
|State||Published - Mar 1 1987|
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