AFM Scanning of Small Molecular Arrays for Rapid Binding Assays

Stuart Lindsay (Inventor), Peiming Zhang (Inventor)

Research output: Patent

Abstract

A method that uses conventional technologies to run binding assays between small chemicals and a target protein at rates of at least 100,000 molecules per minute. The target protein is tethered to an atomic for microscope probe that is canned over an array of small molecules attached to a surface at conventioal imaging speeds whil simultaneously obtaining binding information from the cantilever displacement signal.
Original languageEnglish (US)
StatePublished - Oct 20 2004

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Assays
Scanning
Molecules
Proteins
Microscopes
Imaging techniques

Cite this

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