Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics

Emily A. Higgins Keppler, Carrie L. Jenkins, Trenton J. Davis, Heather Bean

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Due to excellent separation capacity for complex mixtures of chemicals, comprehensive two-dimensional gas chromatography (GC × GC) is being utilized with increasing frequency for metabolomics analyses. This review describes recent advances in GC × GC method development for metabolomics, organismal sampling techniques compatible with GC × GC, metabolomic discoveries made using GC × GC, and recommendations and best practices for collecting and reporting GC × GC metabolomics data.

Original languageEnglish (US)
Pages (from-to)275-286
Number of pages12
JournalTrAC - Trends in Analytical Chemistry
Volume109
DOIs
StatePublished - Dec 1 2018

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Gas chromatography
Complex Mixtures
Sampling
Metabolomics

Keywords

  • Animal models
  • Biospecimens
  • Biotransformation
  • Comprehensive two-dimensional gas chromatography (GC × GC)
  • Data reporting
  • In vitro analyses
  • Metabolomics
  • Multitrophic interactions
  • Sampling

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

Cite this

Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics. / Higgins Keppler, Emily A.; Jenkins, Carrie L.; Davis, Trenton J.; Bean, Heather.

In: TrAC - Trends in Analytical Chemistry, Vol. 109, 01.12.2018, p. 275-286.

Research output: Contribution to journalReview article

Higgins Keppler, Emily A. ; Jenkins, Carrie L. ; Davis, Trenton J. ; Bean, Heather. / Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics. In: TrAC - Trends in Analytical Chemistry. 2018 ; Vol. 109. pp. 275-286.
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