Adult ovary transfer counteracts the callosal enlargement resulting from prepubertal ovariectomy

Heather A. Bimonte, R. Holly Fitch, Victor H. Denenberg

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

The rat corpus callosum (CC) is larger in males than females, and is sensitive to hormone manipulations during development. Previous research found that, in rats, CC sensitivity to testosterone ended by postnatal day 8 (P8). In contrast, more recent findings demonstrated that CC responsivity to ovarian hormones continued at least through P70. The current experiment extends these findings by showing that the female callosum is still sensitive to ovarian hormones as late as P130, well into adulthood. (C) 2000 Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)254-257
Number of pages4
JournalBrain Research
Volume872
Issue number1-2
DOIs
StatePublished - Jul 28 2000
Externally publishedYes

Keywords

  • Corpus callosum
  • Feminization
  • Organizational effects
  • Ovarian hormones
  • Sexual differentiation

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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