TY - JOUR
T1 - Adsorption of alkaloids on ordered mesoporous carbon
AU - Li, Yin
AU - Yuan, Bin
AU - Fu, Jie
AU - Deng, Shuguang
AU - Lu, Xiuyang
N1 - Funding Information:
This work was partially supported by the National Natural Science Foundation of China (No. 21176218 ), the National High Technology Research and Development Program of China (863 Program, No. 2012AA040211 ), and the Hengyi Fund of Zhejiang University. We appreciate Dr. Nataliya U. Tabachkova and Dr. Ilya Krechetov (National University of Science and Technology, “MISiS”, Russia) for obtaining the TEM images for this work. The TEM images were taken in the Joint Research Center of “Material Science and Metallurgy” (NUST, MISiS, Russia) that was funded by The Ministry of Education and Science of the Russian Federation. S. Deng is grateful for the US Department of State for the Fulbright award (Distinguished Chair in Energy Conservation) and his host institute (NUST, MISiS) in Moscow, Russia.
PY - 2013
Y1 - 2013
N2 - An ordered mesoporous carbon (OMC) adsorbent was synthesized, characterized, and evaluated for effective separation and purification of alkaloid compounds from aqueous solutions. The OMC adsorbent has a large BET specific surface area (1532.2 m2/g), large pore volume (2.13 cm3/g), and narrow pore diameter distribution with a median pore diameter of 4.21 nm. Berberine hydrochloride, colchicine, and matrine were selected as the model compounds for evaluating the adsorption properties of the OMC adsorbent for alkaloid purification. Batch adsorption experiments of pure components in water were carried out to measure both adsorption equilibria and kinetics, and column breakthrough and desorption experiments were performed to validate the separation and regeneration efficacy of the OMC adsorbent. The adsorption equilibrium capacities of berberine hydrochloride, colchicine, and matrine on the OMC adsorbent at 0.100 mg/L and 298 K are 450, 600, and 480 mg/g, respectively, which are more than double the adsorption capacities of these compounds on two commonly used commercial resins (HPD300 and HPD100B) at similar conditions. Adsorption equilibrium of all three alkaloids could be obtained within 120 min at 298 K. The dynamic adsorption capacities determined from the breakthrough experiments are within 12% of the estimated equilibrium capacities from the Langmuir isotherms; and 74.3-92.8% of the adsorbed amounts could be recovered by desorbing with a 70% alcohol solution. The adsorption isotherms are analyzed with both Langmuir and Freundlich models, the adsorption kinetic data with the pseudo-first-order and pseudo-second-order models, and the breakthrough curves with four breakthrough models. The large adsorption capacity, fast adsorption rate, and easy regeneration make the ordered mesoporous carbon a promising adsorbent for adsorption and purification of alkaloid compounds from the extracts of herbal plants.
AB - An ordered mesoporous carbon (OMC) adsorbent was synthesized, characterized, and evaluated for effective separation and purification of alkaloid compounds from aqueous solutions. The OMC adsorbent has a large BET specific surface area (1532.2 m2/g), large pore volume (2.13 cm3/g), and narrow pore diameter distribution with a median pore diameter of 4.21 nm. Berberine hydrochloride, colchicine, and matrine were selected as the model compounds for evaluating the adsorption properties of the OMC adsorbent for alkaloid purification. Batch adsorption experiments of pure components in water were carried out to measure both adsorption equilibria and kinetics, and column breakthrough and desorption experiments were performed to validate the separation and regeneration efficacy of the OMC adsorbent. The adsorption equilibrium capacities of berberine hydrochloride, colchicine, and matrine on the OMC adsorbent at 0.100 mg/L and 298 K are 450, 600, and 480 mg/g, respectively, which are more than double the adsorption capacities of these compounds on two commonly used commercial resins (HPD300 and HPD100B) at similar conditions. Adsorption equilibrium of all three alkaloids could be obtained within 120 min at 298 K. The dynamic adsorption capacities determined from the breakthrough experiments are within 12% of the estimated equilibrium capacities from the Langmuir isotherms; and 74.3-92.8% of the adsorbed amounts could be recovered by desorbing with a 70% alcohol solution. The adsorption isotherms are analyzed with both Langmuir and Freundlich models, the adsorption kinetic data with the pseudo-first-order and pseudo-second-order models, and the breakthrough curves with four breakthrough models. The large adsorption capacity, fast adsorption rate, and easy regeneration make the ordered mesoporous carbon a promising adsorbent for adsorption and purification of alkaloid compounds from the extracts of herbal plants.
KW - Adsorption
KW - Alkaloids
KW - Breakthrough
KW - Equilibrium
KW - Kinetics
KW - Ordered mesoporous carbon
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U2 - 10.1016/j.jcis.2013.07.037
DO - 10.1016/j.jcis.2013.07.037
M3 - Article
C2 - 23953651
AN - SCOPUS:84885303632
SN - 0021-9797
VL - 408
SP - 181
EP - 190
JO - Journal of Colloid And Interface Science
JF - Journal of Colloid And Interface Science
IS - 1
ER -