Adaptive introgression underlies polymorphic seasonal camouflage in snowshoe hares

Matthew R. Jones, L. Scott Mills, Paulo Célio Alves, Colin M. Callahan, Joel M. Alves, Diana J.R. Lafferty, Francis M. Jiggins, Jeffrey Jensen, José Melo-Ferreira, Jeffrey M. Good

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Snowshoe hares (Lepus americanus) maintain seasonal camouflage by molting to a white winter coat, but some hares remain brown during the winter in regions with low snow cover. We show that cis-regulatory variation controlling seasonal expression of the Agouti gene underlies this adaptive winter camouflage polymorphism. Genetic variation at Agouti clustered by winter coat color across multiple hare and jackrabbit species, revealing a history of recurrent interspecific gene flow. Brown winter coats in snowshoe hares likely originated from an introgressed black-tailed jackrabbit allele that has swept to high frequency in mild winter environments. These discoveries show that introgression of genetic variants that underlie key ecological traits can seed past and ongoing adaptation to rapidly changing environments.

Original languageEnglish (US)
Pages (from-to)1355-1358
Number of pages4
JournalScience
Volume360
Issue number6395
DOIs
StatePublished - Jun 22 2018

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Hares
Molting
Snow
Gene Flow
Seeds
Color
Alleles
Gene Expression

ASJC Scopus subject areas

  • General

Cite this

Jones, M. R., Scott Mills, L., Alves, P. C., Callahan, C. M., Alves, J. M., Lafferty, D. J. R., ... Good, J. M. (2018). Adaptive introgression underlies polymorphic seasonal camouflage in snowshoe hares. Science, 360(6395), 1355-1358. https://doi.org/10.1126/science.aar5273

Adaptive introgression underlies polymorphic seasonal camouflage in snowshoe hares. / Jones, Matthew R.; Scott Mills, L.; Alves, Paulo Célio; Callahan, Colin M.; Alves, Joel M.; Lafferty, Diana J.R.; Jiggins, Francis M.; Jensen, Jeffrey; Melo-Ferreira, José; Good, Jeffrey M.

In: Science, Vol. 360, No. 6395, 22.06.2018, p. 1355-1358.

Research output: Contribution to journalArticle

Jones, MR, Scott Mills, L, Alves, PC, Callahan, CM, Alves, JM, Lafferty, DJR, Jiggins, FM, Jensen, J, Melo-Ferreira, J & Good, JM 2018, 'Adaptive introgression underlies polymorphic seasonal camouflage in snowshoe hares', Science, vol. 360, no. 6395, pp. 1355-1358. https://doi.org/10.1126/science.aar5273
Jones MR, Scott Mills L, Alves PC, Callahan CM, Alves JM, Lafferty DJR et al. Adaptive introgression underlies polymorphic seasonal camouflage in snowshoe hares. Science. 2018 Jun 22;360(6395):1355-1358. https://doi.org/10.1126/science.aar5273
Jones, Matthew R. ; Scott Mills, L. ; Alves, Paulo Célio ; Callahan, Colin M. ; Alves, Joel M. ; Lafferty, Diana J.R. ; Jiggins, Francis M. ; Jensen, Jeffrey ; Melo-Ferreira, José ; Good, Jeffrey M. / Adaptive introgression underlies polymorphic seasonal camouflage in snowshoe hares. In: Science. 2018 ; Vol. 360, No. 6395. pp. 1355-1358.
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