TY - JOUR
T1 - ACG clinical guideline
T2 - Primary sclerosing cholangitis
AU - Lindor, Keith
AU - Kowdley, Kris V.
AU - Harrison, M. Edwyn
N1 - Publisher Copyright:
© 2015 by the American College of Gastroenterology.
PY - 2015/5/8
Y1 - 2015/5/8
N2 - Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursodeoxycholic acid is used by many on an empiric basis. Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.
AB - Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursodeoxycholic acid is used by many on an empiric basis. Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.
UR - http://www.scopus.com/inward/record.url?scp=84928928414&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84928928414&partnerID=8YFLogxK
U2 - 10.1038/ajg.2015.112
DO - 10.1038/ajg.2015.112
M3 - Article
C2 - 25869391
AN - SCOPUS:84928928414
SN - 0002-9270
VL - 110
SP - 646
EP - 659
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 5
ER -