ACG clinical guideline

Primary sclerosing cholangitis

Keith Lindor, Kris V. Kowdley, M. Edwyn Harrison

Research output: Contribution to journalArticle

148 Citations (Scopus)

Abstract

Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursodeoxycholic acid is used by many on an empiric basis. Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.

Original languageEnglish (US)
Pages (from-to)646-659
Number of pages14
JournalAmerican Journal of Gastroenterology
Volume110
Issue number5
DOIs
StatePublished - May 8 2015

Fingerprint

Bile Duct Neoplasms
Avitaminosis
Ursodeoxycholic Acid
Sclerosing Cholangitis
Metabolic Bone Diseases
Bone Development
Portal Hypertension
Colitis
Liver Transplantation
Liver Diseases
Colon
Fats
Guidelines
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

ACG clinical guideline : Primary sclerosing cholangitis. / Lindor, Keith; Kowdley, Kris V.; Harrison, M. Edwyn.

In: American Journal of Gastroenterology, Vol. 110, No. 5, 08.05.2015, p. 646-659.

Research output: Contribution to journalArticle

Lindor, Keith ; Kowdley, Kris V. ; Harrison, M. Edwyn. / ACG clinical guideline : Primary sclerosing cholangitis. In: American Journal of Gastroenterology. 2015 ; Vol. 110, No. 5. pp. 646-659.
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