ACG clinical guideline: Primary sclerosing cholangitis

Keith Lindor, Kris V. Kowdley, M. Edwyn Harrison

Research output: Contribution to journalArticle

188 Scopus citations

Abstract

Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursodeoxycholic acid is used by many on an empiric basis. Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.

Original languageEnglish (US)
Pages (from-to)646-659
Number of pages14
JournalAmerican Journal of Gastroenterology
Volume110
Issue number5
DOIs
StatePublished - May 8 2015

ASJC Scopus subject areas

  • Gastroenterology

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