ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD

Elena Y. Bryleva, Maximillian A. Rogers, Catherine C.Y. Chang, Floyd Buen, Brent T. Harris, Estelle Rousselet, Nabil G. Seidah, Salvatore Oddo, Frank M. Laferla, Thomas A. Spencer, William F. Hickey, Ta Yuan Chang

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Medicine & Life Sciences