A structural equation modeling approach for the analysis of cortisol data collected using pre-post-post designs

This study introduces a novel application of structural equation modeling (SEM) for the analysis of cortisol data that are collected using a pre-post-post design. By way of an extended example, an SEM model is developed that permits an examination of both the overall level of cortisol, as well as changes in cortisol (reactivity and regulation), as predictors of cognitive (executive) and behavioral functioning in 3- to 5-year-old children (N= 171) attending Head Start. The SEM model makes use of the parameterization of latent curve models. Throughout the extended example, the strengths of using an SEM approach for the analysis of cortisol data that are collected using pre-post-post designs is highlighted.