TY - JOUR
T1 - A simple method to make a membrane with regions of differential permeability
AU - Steve Liu, Ying Horng
AU - Livesay, Eric A.
AU - Luebke, Kevin J.
AU - Johnston, Stephen Albert
N1 - Funding Information:
This work was funded by a grant from the Defense Advanced Research Projects Agency (#N65236-99-1-5426) to Stephen Albert Johnston. Special thanks to the Molecular and Cellular Imaging Facility at the University of Texas Southwestern Medical Center for scanning electron microscopy.
PY - 2003/4/15
Y1 - 2003/4/15
N2 - We describe a method of using heat to produce any pattern of differential permeability in commercially available fluid permeable membranes. An aluminum heating block is machined with specific patterns, heated, and placed in contact with a continuous sheet of polypropylene membrane in order to create impermeable regions in the otherwise permeable membrane. The permeability of the membrane to fluid can be altered by this method in any pattern chosen. Such differentially permeable membranes can be used in high-density, multi-well filtration plates for chemical syntheses or biological assays.
AB - We describe a method of using heat to produce any pattern of differential permeability in commercially available fluid permeable membranes. An aluminum heating block is machined with specific patterns, heated, and placed in contact with a continuous sheet of polypropylene membrane in order to create impermeable regions in the otherwise permeable membrane. The permeability of the membrane to fluid can be altered by this method in any pattern chosen. Such differentially permeable membranes can be used in high-density, multi-well filtration plates for chemical syntheses or biological assays.
KW - Biotechnology
KW - High-density filter plate
KW - Liquid permeability and separations
KW - Microfiltration
KW - Microporous and porous membranes
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U2 - 10.1016/S0376-7388(02)00605-1
DO - 10.1016/S0376-7388(02)00605-1
M3 - Article
AN - SCOPUS:0037445949
SN - 0376-7388
VL - 215
SP - 95
EP - 101
JO - Journal of Membrane Science
JF - Journal of Membrane Science
IS - 1-2
ER -