@article{f762926647a14afd829ef3b0c3c812ff,
title = "A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context",
abstract = "The deployment of gene drives is emerging as an alternative for protecting endangered species, controlling agricultural pests, and reducing vector-borne diseases. This paper reports on a workshop held in February 2016 to explore the complex intersection of political, economic, ethical, and ecological risk issues associated with gene drives. Workshop participants were encouraged to use systems thinking and mapping to describe the connections among social, policy, economic, and ecological variables as they intersect within governance systems. In this paper, we analyze the workshop transcripts and maps using the Institutional Analysis and Development (IAD) framework to categorize variables associated with gene drive governance and account for the complexities of socio-ecological systems. We discuss how the IAD framework can be used in the future to test hypotheses about how features of governance systems might lead to certain outcomes and inform the design of research programs, public engagement, and anticipatory governance of gene drives.",
keywords = "Gene drive, IAD, genetic engineering, governance, risk, systems",
author = "J. Kuzma and F. Gould and Z. Brown and James Collins and J. Delborne and Emma Frow and K. Esvelt and David Guston and C. Leitschuh and K. Oye and S. Stauffer",
note = "Funding Information: The workshop was funded by the Directorate for Social, Behavioral and Economic Sciences, National Science Foundation–Science in Society Program [grant number 1533990] with additional co-funding by the Genetic Engineering and Society Center (GES) at North Carolina State University (NCSU) and the Center for Nanotechnology in Society at Arizona State University. The views, however, are those of the authors and not these institutions. Funding Information: This three-day meeting was funded by the US National Science Foundation (NSF) and held on 24–26 February 2016, prior to the release of the National Academy of Sciences, Engineering, and Medicine report on gene drives (NASEM 2016). The workshop was designed to frame core governance issues and research needs for gene drives within a systems context and focused primarily on the intersection of risk analysis, ethics, policy, and governance. In these ways, it differed from previous workshops on gene drives that have been designed to identify ecological research needs or offer practical policy advice to researchers and regulators (Oye et al. 2014; Carter and Friedman 2016). The meeting was held on 24–26 February 2016, prior to the release of the National Academy of Sciences, Engineering, and Medicine report on gene drives that also makes recommendations about ethics and risk governance (NASEM 2016). Publisher Copyright: {\textcopyright} 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.",
year = "2018",
month = jan,
day = "24",
doi = "10.1080/23299460.2017.1410344",
language = "English (US)",
volume = "5",
pages = "S13--S39",
journal = "Journal of Responsible Innovation",
issn = "2329-9460",
publisher = "Taylor and Francis Ltd.",
}