A review of oral vaccination with transgenic vegetables

Carol O. Tacket; Hugh S. Mason

doi:10.1016/S1286-4579(99)80080-X

A review of oral vaccination with transgenic vegetables

Carol O. Tacket, Hugh S. Mason

Research output: Contribution to journal › Review article › peer-review

57 Scopus citations

Abstract

Mucosal immunization of the gastrointestinal tract is an effective way to stimulate local and systemic immune responses. Oral vaccines must be formulated in such a way that antigens are protected as they pass through the adverse environment of the stomach and are delivered to the mucosal inductive sites. Vaccine antigens cloned into edible transgenic plants are a promising new delivery system for oral vaccines. Such vaccines could be safe, inexpensive, and multicomponent.

Original language	English (US)
Pages (from-to)	777-783
Number of pages	7
Journal	Microbes and Infection
Volume	1
Issue number	10
DOIs	https://doi.org/10.1016/S1286-4579(99)80080-X
State	Published - 1999
Externally published	Yes

Keywords

Edible vaccines
Oral immunization
Transgenic plants

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

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10.1016/S1286-4579(99)80080-X

Cite this

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abstract = "Mucosal immunization of the gastrointestinal tract is an effective way to stimulate local and systemic immune responses. Oral vaccines must be formulated in such a way that antigens are protected as they pass through the adverse environment of the stomach and are delivered to the mucosal inductive sites. Vaccine antigens cloned into edible transgenic plants are a promising new delivery system for oral vaccines. Such vaccines could be safe, inexpensive, and multicomponent.",

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AB - Mucosal immunization of the gastrointestinal tract is an effective way to stimulate local and systemic immune responses. Oral vaccines must be formulated in such a way that antigens are protected as they pass through the adverse environment of the stomach and are delivered to the mucosal inductive sites. Vaccine antigens cloned into edible transgenic plants are a promising new delivery system for oral vaccines. Such vaccines could be safe, inexpensive, and multicomponent.

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KW - Transgenic plants

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A review of oral vaccination with transgenic vegetables

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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