A review of oral vaccination with transgenic vegetables

Carol O. Tacket, Hugh S. Mason

Research output: Contribution to journalReview article

53 Scopus citations

Abstract

Mucosal immunization of the gastrointestinal tract is an effective way to stimulate local and systemic immune responses. Oral vaccines must be formulated in such a way that antigens are protected as they pass through the adverse environment of the stomach and are delivered to the mucosal inductive sites. Vaccine antigens cloned into edible transgenic plants are a promising new delivery system for oral vaccines. Such vaccines could be safe, inexpensive, and multicomponent.

Original languageEnglish (US)
Pages (from-to)777-783
Number of pages7
JournalMicrobes and Infection
Volume1
Issue number10
DOIs
StatePublished - Jan 1 1999
Externally publishedYes

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Keywords

  • Edible vaccines
  • Oral immunization
  • Transgenic plants

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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