A positive genetic correlation between hypoxia tolerance and heat tolerance supports a controversial theory of heat stress

Collin Teague, Jacob P. Youngblood, Kinley Ragan, Michael Angilletta, John M. VandenBrooks

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We used quantitative genetics to test a controversial theory of heat stress, in which animals overheat when the demand for oxygen exceeds the supply. This theory, referred to as oxygen- and capacity-limited thermal tolerance, predicts a positive genetic correlation between hypoxia tolerance and heat tolerance. We demonstrate the first genetic correlation of this kind in a model organism, Drosophila melanogaster. Genotypes more likely to fly under hypoxic stress (12% O2) were also more likely to fly under heat stress (398C). This finding prompts new questions about mechanisms and limits of adaptation to heat stress.

Original languageEnglish (US)
Article number20170309
JournalBiology Letters
Volume13
Issue number11
DOIs
StatePublished - Nov 1 2017

Fingerprint

heat tolerance
genetic correlation
heat stress
hypoxia
Hot Temperature
Oxygen
oxygen
quantitative genetics
Drosophila melanogaster
Genotype
genotype
organisms
Thermotolerance
Hypoxia
animals
testing

Keywords

  • Drosophila
  • Hypoxia
  • Oxygen
  • Performance
  • Temperature
  • Tolerance

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Agricultural and Biological Sciences(all)

Cite this

A positive genetic correlation between hypoxia tolerance and heat tolerance supports a controversial theory of heat stress. / Teague, Collin; Youngblood, Jacob P.; Ragan, Kinley; Angilletta, Michael; VandenBrooks, John M.

In: Biology Letters, Vol. 13, No. 11, 20170309, 01.11.2017.

Research output: Contribution to journalArticle

Teague, Collin ; Youngblood, Jacob P. ; Ragan, Kinley ; Angilletta, Michael ; VandenBrooks, John M. / A positive genetic correlation between hypoxia tolerance and heat tolerance supports a controversial theory of heat stress. In: Biology Letters. 2017 ; Vol. 13, No. 11.
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