A perspective on functionalizing colloidal quantum dots with DNA

Anirban Samanta; Zhengtao Deng; Yan Liu; Hao Yan

doi:10.1007/s12274-013-0367-x

A perspective on functionalizing colloidal quantum dots with DNA

Anirban Samanta, Zhengtao Deng, Yan Liu, Hao Yan

Research output: Contribution to journal › Review article › peer-review

31 Scopus citations

Abstract

This perspective provides an overview of the techniques that have been developed for the conjugation of DNA to colloidal quantum dots (QDs), or semiconductor nanocrystals. Methods described include: ligand exchange at the QD surface, covalent conjugation of DNA to the QD surface ligands, and one-step DNA functionalization on core QDs or during core/shell QD synthesis in aqueous solution, with an emphasis on the most recent progress in our lab. We will also discuss emerging trends in DNA-functionalized QDs for potential applications. [Figure not available: see fulltext.]

Original language	English (US)
Pages (from-to)	853-870
Number of pages	18
Journal	Nano Research
Volume	6
Issue number	12
DOIs	https://doi.org/10.1007/s12274-013-0367-x
State	Published - Dec 2013

Keywords

DNA
colloidal quantum dots
conjugation
core/shell
covalent bond
ligand exchange
semiconductor nanocrystals

ASJC Scopus subject areas

Materials Science(all)
Electrical and Electronic Engineering

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10.1007/s12274-013-0367-x

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title = "A perspective on functionalizing colloidal quantum dots with DNA",

abstract = "This perspective provides an overview of the techniques that have been developed for the conjugation of DNA to colloidal quantum dots (QDs), or semiconductor nanocrystals. Methods described include: ligand exchange at the QD surface, covalent conjugation of DNA to the QD surface ligands, and one-step DNA functionalization on core QDs or during core/shell QD synthesis in aqueous solution, with an emphasis on the most recent progress in our lab. We will also discuss emerging trends in DNA-functionalized QDs for potential applications. [Figure not available: see fulltext.]",

keywords = "DNA, colloidal quantum dots, conjugation, core/shell, covalent bond, ligand exchange, semiconductor nanocrystals",

author = "Anirban Samanta and Zhengtao Deng and Yan Liu and Hao Yan",

note = "Funding Information: The authors acknowledge the grant support from the Office of Naval Research (ONR) to YL and ZD, and the National Science Foundation (NSF) to HY and YL. We also thank Dr. Jeanette Nangreave for assistance in proofreading the manuscript.",

year = "2013",

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doi = "10.1007/s12274-013-0367-x",

language = "English (US)",

volume = "6",

pages = "853--870",

journal = "Nano Research",

issn = "1998-0124",

publisher = "Press of Tsinghua University",

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T1 - A perspective on functionalizing colloidal quantum dots with DNA

AU - Samanta, Anirban

AU - Deng, Zhengtao

AU - Liu, Yan

AU - Yan, Hao

N1 - Funding Information: The authors acknowledge the grant support from the Office of Naval Research (ONR) to YL and ZD, and the National Science Foundation (NSF) to HY and YL. We also thank Dr. Jeanette Nangreave for assistance in proofreading the manuscript.

PY - 2013/12

Y1 - 2013/12

N2 - This perspective provides an overview of the techniques that have been developed for the conjugation of DNA to colloidal quantum dots (QDs), or semiconductor nanocrystals. Methods described include: ligand exchange at the QD surface, covalent conjugation of DNA to the QD surface ligands, and one-step DNA functionalization on core QDs or during core/shell QD synthesis in aqueous solution, with an emphasis on the most recent progress in our lab. We will also discuss emerging trends in DNA-functionalized QDs for potential applications. [Figure not available: see fulltext.]

AB - This perspective provides an overview of the techniques that have been developed for the conjugation of DNA to colloidal quantum dots (QDs), or semiconductor nanocrystals. Methods described include: ligand exchange at the QD surface, covalent conjugation of DNA to the QD surface ligands, and one-step DNA functionalization on core QDs or during core/shell QD synthesis in aqueous solution, with an emphasis on the most recent progress in our lab. We will also discuss emerging trends in DNA-functionalized QDs for potential applications. [Figure not available: see fulltext.]

KW - DNA

KW - colloidal quantum dots

KW - conjugation

KW - core/shell

KW - covalent bond

KW - ligand exchange

KW - semiconductor nanocrystals

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JO - Nano Research

JF - Nano Research

IS - 12

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A perspective on functionalizing colloidal quantum dots with DNA

Abstract

Keywords

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