A parasite outbreak in notothenioid fish in an Antarctic fjord

Thomas Desvignes, Henrik Lauridsen, Alejandro Valdivieso, Rafaela S. Fontenele, Simona Kraberger, Katrina N. Murray, Nathalie R. Le François, H. William Detrich, Michael L. Kent, Arvind Varsani, John H. Postlethwait

Research output: Contribution to journalArticlepeer-review

Abstract

Climate changes can promote disease outbreaks, but their nature and potential impacts in remote areas have received little attention. In a hot spot of biodiversity on the West Antarctic Peninsula, which faces among the fastest changing climates on Earth, we captured specimens of two notothenioid fish species affected by large skin tumors at an incidence never before observed in the Southern Ocean. Molecular and histopathological analyses revealed that X-cell parasitic alveolates, members of a genus we call Notoxcellia, are the etiological agent of these tumors. Parasite-specific molecular probes showed that xenomas remained within the skin but largely outgrew host cells in the dermis. We further observed that tumors induced neovascularization in underlying tissue and detrimentally affected host growth and condition. Although many knowledge gaps persist about X-cell disease, including its mode of transmission and life cycle, these findings reveal potentially active biotic threats to vulnerable Antarctic ecosystems.

Original languageEnglish (US)
Article number104588
JournaliScience
Volume25
Issue number7
DOIs
StatePublished - Jul 15 2022
Externally publishedYes

Keywords

  • Biological sciences
  • Microbiology
  • Microbiology parasite
  • Parasitology
  • Zoology

ASJC Scopus subject areas

  • General

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