A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV).

K. Nazerian, E. A. Stephens, J. M. Sharma, L. F. Lee, M. Gailitis, R. L. Witter

Research output: Contribution to journalArticle

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Abstract

A continuous lymphoblastoid cell line was established from a JMV tumor transplant related to Marek's disease (MD). It is designated RPL1 (JMV) lymphoblastoid cell line. This cell line contains DNA sequences complementary to MD virus DNA and has an antigen similar to MD-tumor-associated surface antigen (MATSA). However, it lacks any MD virus (MDV) rescuable in vivo or in vitro. The cell line has surface antigens typical of chicken thymus cells (T cells) and histocompatability antigens different from those of the host chicken.

Original languageEnglish (US)
Pages (from-to)69-76
Number of pages8
JournalAvian Diseases
Volume21
Issue number1
StatePublished - Jan 1977
Externally publishedYes

Fingerprint

Marek Disease
Marek disease
T-lymphocytes
cell lines
Cell Line
Mardivirus
neoplasms
surface antigens
Surface Antigens
Chickens
Neoplasms
chickens
antigens
Antigens
DNA Viruses
Thymus Gland
Viruses
Transplants
nucleotide sequences
DNA

ASJC Scopus subject areas

  • Cancer Research
  • Immunology
  • veterinary(all)

Cite this

Nazerian, K., Stephens, E. A., Sharma, J. M., Lee, L. F., Gailitis, M., & Witter, R. L. (1977). A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV). Avian Diseases, 21(1), 69-76.

A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV). / Nazerian, K.; Stephens, E. A.; Sharma, J. M.; Lee, L. F.; Gailitis, M.; Witter, R. L.

In: Avian Diseases, Vol. 21, No. 1, 01.1977, p. 69-76.

Research output: Contribution to journalArticle

Nazerian, K, Stephens, EA, Sharma, JM, Lee, LF, Gailitis, M & Witter, RL 1977, 'A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV).', Avian Diseases, vol. 21, no. 1, pp. 69-76.
Nazerian K, Stephens EA, Sharma JM, Lee LF, Gailitis M, Witter RL. A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV). Avian Diseases. 1977 Jan;21(1):69-76.
Nazerian, K. ; Stephens, E. A. ; Sharma, J. M. ; Lee, L. F. ; Gailitis, M. ; Witter, R. L. / A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV). In: Avian Diseases. 1977 ; Vol. 21, No. 1. pp. 69-76.
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