A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV).

K. Nazerian; E. A. Stephens; J. M. Sharma; L. F. Lee; M. Gailitis; R. L. Witter

doi:10.2307/1589365

A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV).

K. Nazerian, E. A. Stephens, J. M. Sharma, L. F. Lee, M. Gailitis, R. L. Witter

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

A continuous lymphoblastoid cell line was established from a JMV tumor transplant related to Marek's disease (MD). It is designated RPL1 (JMV) lymphoblastoid cell line. This cell line contains DNA sequences complementary to MD virus DNA and has an antigen similar to MD-tumor-associated surface antigen (MATSA). However, it lacks any MD virus (MDV) rescuable in vivo or in vitro. The cell line has surface antigens typical of chicken thymus cells (T cells) and histocompatability antigens different from those of the host chicken.

Original language	English (US)
Pages (from-to)	69-76
Number of pages	8
Journal	Avian diseases
Volume	21
Issue number	1
DOIs	https://doi.org/10.2307/1589365
State	Published - 1977
Externally published	Yes

ASJC Scopus subject areas

Food Animals
Animal Science and Zoology
General Immunology and Microbiology

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abstract = "A continuous lymphoblastoid cell line was established from a JMV tumor transplant related to Marek's disease (MD). It is designated RPL1 (JMV) lymphoblastoid cell line. This cell line contains DNA sequences complementary to MD virus DNA and has an antigen similar to MD-tumor-associated surface antigen (MATSA). However, it lacks any MD virus (MDV) rescuable in vivo or in vitro. The cell line has surface antigens typical of chicken thymus cells (T cells) and histocompatability antigens different from those of the host chicken.",

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AU - Nazerian, K.

AU - Stephens, E. A.

AU - Sharma, J. M.

AU - Lee, L. F.

AU - Gailitis, M.

AU - Witter, R. L.

PY - 1977

Y1 - 1977

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AB - A continuous lymphoblastoid cell line was established from a JMV tumor transplant related to Marek's disease (MD). It is designated RPL1 (JMV) lymphoblastoid cell line. This cell line contains DNA sequences complementary to MD virus DNA and has an antigen similar to MD-tumor-associated surface antigen (MATSA). However, it lacks any MD virus (MDV) rescuable in vivo or in vitro. The cell line has surface antigens typical of chicken thymus cells (T cells) and histocompatability antigens different from those of the host chicken.

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A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV).

Abstract

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