A new method for the synthesis of nitriles from amides under non-acidic conditions

Marcos L. Sznaidman, Curtis Crasto, Sidney M. Hecht

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Aryl carboxamides and other electron rich amides were converted to the respective nitriles in good yields by treatment with Ag2O and C2H5I in benzene at reflux.

Original languageEnglish (US)
Pages (from-to)1581-1584
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number10
DOIs
StatePublished - Mar 5 1993
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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