A multiparametric biosensor array for on-chip cell culture with feedback controlled microfluidics

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

We present work towards expanding the capabilities of microfluidic cell culture devices through the incorporation of microelectronic sensing systems. A system has been fabricated that includes four sensing regions each consisting of a pH sensor, capacitance sensor, and photodiode. We have demonstrated the incorporation of feedback control systems using computer controlled microfluidics for a pH sensor. Preliminary data for photodiode characterization, pH detection using ISFETs, and capacitance sensing of cell density is presented. Results from this work will be used towards creating a single system that can function as a cell culture platform with programmable control over all of these variables.

Original languageEnglish (US)
Title of host publication2011 IEEE International Symposium of Circuits and Systems, ISCAS 2011
Pages809-812
Number of pages4
DOIs
StatePublished - Aug 2 2011
Event2011 IEEE International Symposium of Circuits and Systems, ISCAS 2011 - Rio de Janeiro, Brazil
Duration: May 15 2011May 18 2011

Publication series

NameProceedings - IEEE International Symposium on Circuits and Systems
ISSN (Print)0271-4310

Other

Other2011 IEEE International Symposium of Circuits and Systems, ISCAS 2011
CountryBrazil
CityRio de Janeiro
Period5/15/115/18/11

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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    Welch, D., & Blain Christen, J. (2011). A multiparametric biosensor array for on-chip cell culture with feedback controlled microfluidics. In 2011 IEEE International Symposium of Circuits and Systems, ISCAS 2011 (pp. 809-812). [5937689] (Proceedings - IEEE International Symposium on Circuits and Systems). https://doi.org/10.1109/ISCAS.2011.5937689