TY - JOUR
T1 - A group contribution method for the estimation of equilibrium constants for biochemical reactions
AU - Mavrovouniotis, Michael L.
AU - Bayol, Patrick
AU - Lam, Tu Kien Michael
AU - Stephanopoulos, George
AU - Stephanopoulos, Gregory
PY - 1988/3
Y1 - 1988/3
N2 - Using Gibbs Energies of compounds, as well as Gibbs Energy changes and equilibrium constants of biochemical reactions, the contributions of functional groups to the Gibbs Energy (in aqueous solution, temperature 25°C, and pH=7) have been estimated. These contributions allow the estimation of the Gibbs Free Energy and the equilibrium constant of a biochemical reaction, given the structure of the reactants and products.
AB - Using Gibbs Energies of compounds, as well as Gibbs Energy changes and equilibrium constants of biochemical reactions, the contributions of functional groups to the Gibbs Energy (in aqueous solution, temperature 25°C, and pH=7) have been estimated. These contributions allow the estimation of the Gibbs Free Energy and the equilibrium constant of a biochemical reaction, given the structure of the reactants and products.
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U2 - 10.1007/BF01874203
DO - 10.1007/BF01874203
M3 - Article
AN - SCOPUS:15844389188
SN - 0951-208X
VL - 2
SP - 23
EP - 28
JO - Biotechnology Techniques
JF - Biotechnology Techniques
IS - 1
ER -