A genetic comparison of two alleged subspecies of Philippine cynomolgus macaques

David Glenn Smith, Jillian Ng, Debra George, Jessica Satkoski Trask, Paul Houghton, Balbir Singh, Jason Villano, Sreetharan Kanthaswamy

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Two subspecies of cynomolgus macaques (Macaca fascicularis) are alleged to co-exist in the Philippines, M. f. philippensis in the north and M. f. fascicularis in the south. However, genetic differences between the cynomolgus macaques in the two regions have never been studied to document the propriety of their subspecies status. We genotyped samples of cynomolgus macaques from Batangas in southwestern Luzon and Zamboanga in southwestern Mindanao for 15 short tandem repeat (STR) loci and sequenced an 835 bp fragment of the mtDNA of these animals. The STR genotypes were compared with those of cynomolgus macaques from southern Sumatra, Singapore, Mauritius and Cambodia, and the mtDNA sequences of both Philippine populations were compared with those of cynomolgus macaques from southern Sumatra, Indonesia and Sarawak, Malaysia. We conducted STRUCTURE and PCA analyses based on the STRs and constructed a median joining network based on the mtDNA sequences. The Philippine population from Batangas exhibited much less genetic diversity and greater genetic divergence from all other populations, including the Philippine population from Zamboanga. Sequences from both Batangas and Zamboanga were most closely related to two different mtDNA haplotypes from Sarawak from which they are apparently derived. Those from Zamboanga were more recently derived than those from Batangas, consistent with their later arrival in the Philippines. However, clustering analyses do not support a sufficient genetic distinction of cynomolgus macaques from Batangas from other regional populations assigned to subspecies M. f. fascicularis to warrant the subspecies distinction M. f. philippensis. Am J Phys Anthropol 155:136-148, 2014.

Original languageEnglish (US)
Pages (from-to)136-148
Number of pages13
JournalAmerican Journal of Physical Anthropology
Volume155
Issue number1
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Philippines
Macaca
Mitochondrial DNA
Indonesia
Malaysia
Population
Microsatellite Repeats
Mauritius
Cambodia
Passive Cutaneous Anaphylaxis
Macaca fascicularis
Singapore
divergence
Haplotypes
animal
Cluster Analysis
Genotype

Keywords

  • Macaca fascicularis
  • mitochondrial DNA
  • short tandem repeat (STR)
  • subspecies

ASJC Scopus subject areas

  • Anthropology
  • Anatomy

Cite this

A genetic comparison of two alleged subspecies of Philippine cynomolgus macaques. / Smith, David Glenn; Ng, Jillian; George, Debra; Trask, Jessica Satkoski; Houghton, Paul; Singh, Balbir; Villano, Jason; Kanthaswamy, Sreetharan.

In: American Journal of Physical Anthropology, Vol. 155, No. 1, 2014, p. 136-148.

Research output: Contribution to journalArticle

Smith, DG, Ng, J, George, D, Trask, JS, Houghton, P, Singh, B, Villano, J & Kanthaswamy, S 2014, 'A genetic comparison of two alleged subspecies of Philippine cynomolgus macaques', American Journal of Physical Anthropology, vol. 155, no. 1, pp. 136-148. https://doi.org/10.1002/ajpa.22564
Smith, David Glenn ; Ng, Jillian ; George, Debra ; Trask, Jessica Satkoski ; Houghton, Paul ; Singh, Balbir ; Villano, Jason ; Kanthaswamy, Sreetharan. / A genetic comparison of two alleged subspecies of Philippine cynomolgus macaques. In: American Journal of Physical Anthropology. 2014 ; Vol. 155, No. 1. pp. 136-148.
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