A contour-mode film bulk acoustic resonator for monitoring blood coagulation in real-time

W. Xu, J. Appel, Junseok Chae

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

We report a MEMS contour-mode film bulk acoustic resonator (C-FBAR) to monitor whole blood coagulation in-vitro in real time. The C-FBAR has a suspended ring of piezoelectric aluminum nitride excited in the radial-extensional mode. It operates at its resonant frequency of 150 MHz and possesses a quality factor (Q) of 140 in water. The C-FBAR is characterized using aqueous glycerine solutions showing that it accurately measures the viscosity in the range of 1 to 10 centipoises. The C-FBAR, then, is used to monitor blood coagulation in-vitro in real time. The resonant frequency decreases as viscosity of the blood increases during the fibrin creation after the coagulation cascade. The coagulation time and the start/end of the fibrin creation are determined, suggesting the C-FBAR as a potentially low-cost, portable tool for hemostasis diagnostics.

Original languageEnglish (US)
Title of host publication2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages2871-2874
Number of pages4
DOIs
StatePublished - 2011
Event2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China
Duration: Jun 5 2011Jun 9 2011

Publication series

Name2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Other

Other2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Country/TerritoryChina
CityBeijing
Period6/5/116/9/11

Keywords

  • Blood coagulation
  • Resonators
  • Viscosity sensorf

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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