A catalytic RNA and its gene from Salmonella typhimurium

Madeline Baer, Sidney Altman

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

The gene for the RNA subunit (M1 RNA) of ribonuclease P from Salmonella typhimurium directs the synthesis of an RNA that can cleave transfer RNA precursor molecules. The mature M1 RNA coded for by Salmonella typhimurium is 375 nucleotides long and has six nucleotide changes in comparison to M1 RNA from Escherichia coli. The regions for promotion and termination of transcription are closely conserved, but adjacent regions of nucleotide sequences show considerable drift.

Original languageEnglish (US)
Pages (from-to)999-1002
Number of pages4
JournalScience
Volume228
Issue number4702
DOIs
StatePublished - Jan 1 1985
Externally publishedYes

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