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  • John Spence
Article

7 Å resolution in protein twodimensional-crystal X-ray diffraction at Linac Coherent Light Source

Pedrini, B., Tsai, C. J., Capitani, G., Padeste, C., Hunter, M. S., Zatsepin, N., Barty, A., Henry Benner, W., Boutet, S., Feld, G. K., Hau-Riege, S. P., Kirian, R., Kupitz, C., Messerschmitt, M., Ogren, J. I., Pardini, T., Segelke, B., Williams, G. J., Spence, J., Abela, R. & 5 others, Coleman, M., Evans, J. E., Schertler, G. F. X., Frank, M. & Li, X. D., Jul 17 2014, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1647, 20130500.

Research output: Contribution to journalArticle

29 Scopus citations

Ab-initio phasing using nanocrystal shape transforms with incomplete unit cells

Liu, H., Zatsepin, N. & Spence, J., Jan 1 2014, In : IUCrJ. 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

A novel inert crystal delivery medium for serial femtosecond crystallography

Conrad, C. E., Basu, S., James, D., Wang, D., Schaffer, A., Roy-Chowdhury, S., Zatsepin, N., Aquila, A., Coe, J., Gati, C., Hunter, M. S., Koglin, J. E., Kupitz, C., Nelson, G., Subramanian, G., White, T. A., Zhao, Y., Zook, J., Boutet, S., Cherezov, V. & 4 others, Spence, J., Fromme, R., Weierstall, U. & Fromme, P., Jul 1 2015, In : IUCrJ. 2, p. 421-430 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

Approaches to time-resolved diffraction using an XFEL

Spence, J., Dec 1 2014, In : Faraday Discussions. 171, p. 429-438 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Automatic recovery of missing amplitudes and phases in tilt-limited electron crystallography of two-dimensional crystals

Gipson, B. R., Masiel, D. J., Browning, N. D., Spence, J., Mitsuoka, K. & Stahlberg, H., Jul 22 2011, In : Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 84, 1, 011916.

Research output: Contribution to journalArticle

18 Scopus citations

Casimir torque between birefringent plates with metamaterials

Chen, X. & Spence, J., Sep 2013, In : Physica Status Solidi (A) Applications and Materials Science. 210, 9, p. 1925-1932 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Coherent convergent-beam time-resolved X-ray diffraction

Spence, J., Zatsepin, N. & Li, C., Jul 17 2014, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1647, 20130325.

Research output: Contribution to journalArticle

11 Scopus citations

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Kang, Y., Zhou, X. E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., White, T. A., Yefanov, O., Han, G. W., Xu, Q., De Waal, P. W., Ke, J., Tan, M. H. E., Zhang, C., Moeller, A., West, G. M., Pascal, B. D., Van Eps, N., Caro, L. N. & 52 others, Vishnivetskiy, S. A., Lee, R. J., Suino-Powell, K. M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G. J., Messerschmidt, M., Gati, C., Zatsepin, N., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C. E., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C. S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H. N., Spence, J., Fromme, P., Weierstall, U., Ernst, O. P., Katritch, V., Gurevich, V. V., Griffin, P. R., Hubbell, W. L., Stevens, R. C., Cherezov, V., Melcher, K. & Xu, H. E., Jul 30 2015, In : Nature. 523, 7562, p. 561-567 7 p.

Research output: Contribution to journalArticle

436 Scopus citations

Data collection strategies for time-resolved X-ray free-electron laser diffraction, and 2-color methods

Li, C., Schmidt, K. & Spence, J., Jul 1 2015, In : Structural Dynamics. 2, 4, 041714.

Research output: Contribution to journalArticle

7 Scopus citations

Direct phasing in femtosecond nanocrystallography. I. Diffraction characteristics

Chen, J. P. J., Spence, J. & Millane, R. P., Mar 2014, In : Acta Crystallographica Section A: Foundations and Advances. 70, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Direct phasing in femtosecond nanocrystallography. II. Phase retrieval

Chen, J. P. J., Spence, J. & Millane, R. P., Mar 2014, In : Acta Crystallographica Section A: Foundations and Advances. 70, 2, p. 154-161 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
4 Scopus citations

Double-focusing mixing jet for XFEL study of chemical kinetics

Wang, D., Weierstall, U., Pollack, L. & Spence, J., Nov 1 2014, In : Journal of synchrotron radiation. 21, 6, p. 1364-1366 3 p.

Research output: Contribution to journalArticle

48 Scopus citations

Electronic damage in S atoms in a native protein crystal induced by an intense X-ray free-electron laser pulse

Galli, L., Son, S. K., Klinge, M., Bajt, S., Barty, A., Bean, R., Betzel, C., Beyerlein, K. R., Caleman, C., Doak, R. B., Duszenko, M., Fleckenstein, H., Gati, C., Hunt, B., Kirian, R., Liang, M., Nanao, M. H., Nass, K., Oberthür, D., Redecke, L. & 7 others, Shoeman, R., Stellato, F., Yoon, C. H., White, T. A., Yefanov, O., Spence, J. & Chapman, H. N., Jul 1 2015, In : Structural Dynamics. 2, 4, 041703.

Research output: Contribution to journalArticle

11 Scopus citations

Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography

Olmos, J. L., Pandey, S., Martin-Garcia, J. M., Calvey, G., Katz, A., Knoska, J., Kupitz, C., Hunter, M. S., Liang, M., Oberthuer, D., Yefanov, O., Wiedorn, M., Heyman, M., Holl, M., Pande, K., Barty, A., Miller, M. D., Stern, S., Roy-Chowdhury, S., Coe, J. & 30 others, Nagaratnam, N., Zook, J., Verburgt, J., Norwood, T., Poudyal, I., Xu, D., Koglin, J., Seaberg, M. H., Zhao, Y., Bajt, S., Grant, T., Mariani, V., Nelson, G., Subramanian, G., Bae, E., Fromme, R., Fung, R., Schwander, P., Frank, M., White, T. A., Weierstall, U., Zatsepin, N., Spence, J., Fromme, P., Chapman, H. N., Pollack, L., Tremblay, L., Ourmazd, A., Phillips, G. N. & Schmidt, M., May 31 2018, In : BMC Biology. 16, 1, 59.

Research output: Contribution to journalArticle

41 Scopus citations

Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1

Lee, H. H., Cherni, I., Yu, H., Fromme, R., Doran, J. D., Grotjohann, I., Mittman, M., Basu, S., Deb, A., Dörner, K., Aquila, A., Barty, A., Boutet, S., Chapman, H. N., Doak, R. B., Hunter, M. S., James, D., Kirian, R., Kupitz, C., Lawrence, R. M. & 17 others, Liu, H., Nass, K., Schlichting, I., Schmidt, K., Seibert, M. M., Shoeman, R. L., Spence, J., Stellato, F., Weierstall, U., Williams, G. J., Yoon, C., Wang, D., Zatsepin, N., Hogue, B., Matoba, N., Fromme, P. & Leket-Mor, T., Aug 29 2014, In : IUCrJ. 1, p. 305-317 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Femtosecond free-electron laser X-ray diffraction data sets for algorithm development

Kassemeyer, S., Steinbrener, J., Lomb, L., Hartmann, E., Aquila, A., Barty, A., Martin, A. V., Hampton, C. Y., Bajt, S., Barthelmess, M., Barends, T. R. M., Bostedt, C., Bott, M., Bozek, J. D., Coppola, N., Cryle, M., De Ponte, D. P., Doak, R. B., Epp, S. W., Erk, B. & 42 others, Fleckenstein, H., Foucar, L., Graafsma, H., Gumprecht, L., Hartmann, A., Hartmann, R., Hauser, G., Hirsemann, H., Hömke, A., Holl, P., Jönsson, O., Kimmel, N., Krasniqi, F., Liang, M., Maia, F. R. N. C., Marchesini, S., Nass, K., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schmidt, C., Schulz, J., Shoeman, R. L., Sierra, R. G., Soltau, H., Spence, J., Starodub, D., Stellato, F., Stern, S., Stier, G., Svenda, M., Weidenspointner, G., Weierstall, U., White, T. A., Wunderer, C., Frank, M., Chapman, H. N., Ullrich, J., Strüder, L., Bogan, M. J. & Schlichting, I., Feb 13 2012, In : Optics Express. 20, 4, p. 4149-4158 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein

Pande, K., Hutchison, C. D. M., Groenhof, G., Aquila, A., Robinson, J. S., Tenboer, J., Basu, S., Boutet, S., DePonte, D. P., Liang, M., White, T. A., Zatsepin, N., Yefanov, O., Morozov, D., Oberthuer, D., Gati, C., Subramanian, G., James, D., Zhao, Y., Koralek, J. & 24 others, Brayshaw, J., Kupitz, C., Conrad, C., Roy-Chowdhury, S., Coe, J. D., Metz, M., Xavier, P. L., Grant, T. D., Koglin, J. E., Ketawala, G., Fromme, R., Srajer, V., Henning, R., Spence, J., Ourmazd, A., Schwander, P., Weierstall, U., Frank, M., Fromme, P., Barty, A., Chapman, H. N., Moffat, K., Van Thor, J. J. & Schmidt, M., May 6 2016, In : Science. 352, 6286, p. 725-729 5 p.

Research output: Contribution to journalArticle

201 Scopus citations

Femtosecond X-ray diffraction from two-dimensional protein crystals

Frank, M., Carlson, D. B., Hunter, M. S., Williams, G. J., Messerschmidt, M., Zatsepin, N., Barty, A., Benner, W. H., Chu, K., Graf, A. T., Hau-Riege, S. P., Kirian, R., Padeste, C., Pardini, T., Pedrini, B., Segelke, B., Seibert, M. M., Spence, J., Tsai, C. J., Lane, S. M. & 5 others, Li, X. D., Schertler, G., Boutet, S., Coleman, M. & Evans, J. E., Feb 28 2014, In : IUCrJ. 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Femtosecond X-ray protein nanocrystallography

Chapman, H. N., Fromme, P., Barty, A., White, T. A., Kirian, R., Aquila, A., Hunter, M. S., Schulz, J., Deponte, D. P., Weierstall, U., Doak, R. B., Maia, F. R. N. C., Martin, A. V., Schlichting, I., Lomb, L., Coppola, N., Shoeman, R. L., Epp, S. W., Hartmann, R., Rolles, D. & 68 others, Rudenko, A., Foucar, L., Kimmel, N., Weidenspointner, G., Holl, P., Liang, M., Barthelmess, M., Caleman, C., Boutet, S., Bogan, M. J., Krzywinski, J., Bostedt, C., Bajt, S., Gumprecht, L., Rudek, B., Erk, B., Schmidt, C., Hömke, A., Reich, C., Pietschner, D., Ströder, L., Hauser, G., Gorke, H., Ullrich, J., Herrmann, S., Schaller, G., Schopper, F., Soltau, H., Kühnel, K. U., Messerschmidt, M., Bozek, J. D., Hau-Riege, S. P., Frank, M., Hampton, C. Y., Sierra, R. G., Starodub, D., Williams, G. J., Hajdu, J., Timneanu, N., Seibert, M. M., Andreasson, J., Rocker, A., Jönsson, O., Svenda, M., Stern, S., Nass, K., Andritschke, R., Schröter, C. D., Krasniqi, F., Bott, M., Schmidt, K., Wang, X., Grotjohann, I., Holton, J. M., Barends, T. R. M., Neutze, R., Marchesini, S., Fromme, R., Schorb, S., Rupp, D., Adolph, M., Gorkhover, T., Andersson, I., Hirsemann, H., Potdevin, G., Graafsma, H., Nilsson, B. & Spence, J., Feb 3 2011, In : Nature. 470, 7332, p. 73-78 6 p.

Research output: Contribution to journalArticle

1316 Scopus citations

High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography

Boutet, S., Lomb, L., Williams, G. J., Barends, T. R. M., Aquila, A., Doak, R. B., Weierstall, U., DePonte, D. P., Steinbrener, J., Shoeman, R. L., Messerschmidt, M., Barty, A., White, T. A., Kassemeyer, S., Kirian, R., Seibert, M. M., Montanez, P. A., Kenney, C., Herbst, R., Hart, P. & 34 others, Pines, J., Haller, G., Gruner, S. M., Philipp, H. T., Tate, M. W., Hromalik, M., Koerner, L. J., Van Bakel, N., Morse, J., Ghonsalves, W., Arnlund, D., Bogan, M. J., Caleman, C., Fromme, R., Hampton, C. Y., Hunter, M. S., Johansson, L. C., Katona, G., Kupitz, C., Liang, M., Martin, A. V., Nass, K., Redecke, L., Stellato, F., Timneanu, N., Wang, D., Zatsepin, N., Schafer, D., Defever, J., Neutze, R., Fromme, P., Spence, J., Chapman, H. N. & Schlichting, I., Jul 20 2012, In : Science. 337, 6092, p. 362-364 3 p.

Research output: Contribution to journalArticle

549 Scopus citations

Hollow cone illumination for fast TEM, and outrunning damage with electrons

Spence, J., Subramanian, G. & Musumeci, P., Sep 23 2015, In : Journal of Physics B: Atomic, Molecular and Optical Physics. 48, 21, 214003.

Research output: Contribution to journalArticle

12 Scopus citations

In situ EELS study of dehydration of Al(OH)3 by electron beam irradiation

Jiang, N. & Spence, J., Jun 1 2011, In : Ultramicroscopy. 111, 7, p. 860-864 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

In vivo protein crystallization opens new routes in structural biology

Koopmann, R., Cupelli, K., Redecke, L., Nass, K., Deponte, D. P., White, T. A., Stellato, F., Rehders, D., Liang, M., Andreasson, J., Aquila, A., Bajt, S., Barthelmess, M., Barty, A., Bogan, M. J., Bostedt, C., Boutet, S., Bozek, J. D., Caleman, C., Coppola, N. & 49 others, Davidsson, J., Doak, R. B., Ekeberg, T., Epp, S. W., Erk, B., Fleckenstein, H., Foucar, L., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C. Y., Hartmann, A., Hartmann, R., Hauser, G., Hirsemann, H., Holl, P., Hunter, M. S., Kassemeyer, S., Kirian, R., Lomb, L., Maia, F. R. N. C., Kimmel, N., Martin, A. V., Messerschmidt, M., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schlichting, I., Schulz, J., Seibert, M. M., Shoeman, R. L., Sierra, R. G., Soltau, H., Stern, S., Strülder, L., Timneanu, N., Ullrich, J., Wang, X., Weidenspointner, G., Weierstall, U., Williams, G. J., Wunderer, C. B., Fromme, P., Spence, J., Stehle, T., Chapman, H. N., Betzel, C. & Duszenko, M., Mar 2012, In : Nature Methods. 9, 3, p. 259-262 4 p.

Research output: Contribution to journalArticle

131 Scopus citations

Lawrence Bragg, microdiffraction and X-ray lasers

Spence, J., Jan 1 2013, In : Acta Crystallographica Section A: Foundations of Crystallography. 69, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

Weierstall, U., James, D., Wang, C., White, T. A., Wang, D., Liu, W., Spence, J., Bruce Doak, R., Nelson, G., Fromme, P., Fromme, R., Grotjohann, I., Kupitz, C., Zatsepin, N., Liu, H., Basu, S., Wacker, D., Won Han, G., Katritch, V., Boutet, S. & 17 others, Messerschmidt, M., Williams, G. J., Koglin, J. E., Marvin Seibert, M., Klinker, M., Gati, C., Shoeman, R. L., Barty, A., Chapman, H. N., Kirian, R., Beyerlein, K. R., Stevens, R. C., Li, D., Shah, S. T. A., Howe, N., Caffrey, M. & Cherezov, V., Feb 14 2014, In : Nature communications. 5, 3309.

Research output: Contribution to journalArticle

335 Scopus citations

Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography

Nogly, P., Panneels, V., Nelson, G., Gati, C., Kimura, T., Milne, C., Milathianaki, D., Kubo, M., Wu, W., Conrad, C., Coe, J., Bean, R., Zhao, Y., Båth, P., Dods, R., Harimoorthy, R., Beyerlein, K. R., Rheinberger, J., James, D., DePonte, D. & 20 others, Li, C., Sala, L., Williams, G. J., Hunter, M. S., Koglin, J. E., Berntsen, P., Nango, E., Iwata, S., Chapman, H. N., Fromme, P., Frank, M., Abela, R., Boutet, S., Barty, A., White, T. A., Weierstall, U., Spence, J., Neutze, R., Schertler, G. & Standfuss, J., Aug 22 2016, In : Nature communications. 7, 12314.

Research output: Contribution to journalArticle

45 Scopus citations

Lipidic cubic phase serial millisecond crystallography using synchrotron radiation

Nogly, P., James, D., Wang, D., White, T. A., Zatsepin, N., Shilova, A., Nelson, G., Liu, H., Johansson, L., Heymann, M., Jaeger, K., Metz, M., Wickstrand, C., Wu, W., Båth, P., Berntsen, P., Oberthuer, D., Panneels, V., Cherezov, V., Chapman, H. & 7 others, Schertler, G., Neutze, R., Spence, J., Moraes, I., Burghammer, M., Standfuss, J. & Weierstall, U., Feb 26 2015, In : IUCrJ. 2, p. 168-176 9 p.

Research output: Contribution to journalArticle

122 Scopus citations

Lipidic phase membrane protein serial femtosecond crystallography

Johansson, L. C., Arnlund, D., White, T. A., Katona, G., Deponte, D. P., Weierstall, U., Doak, R. B., Shoeman, R. L., Lomb, L., Malmerberg, E., Davidsson, J., Nass, K., Liang, M., Andreasson, J., Aquila, A., Bajt, S., Barthelmess, M., Barty, A., Bogan, M. J., Bostedt, C. & 48 others, Bozek, J. D., Caleman, C., Coffee, R., Coppola, N., Ekeberg, T., Epp, S. W., Erk, B., Fleckenstein, H., Foucar, L., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C. Y., Hartmann, R., Hartmann, A., Hauser, G., Hirsemann, H., Holl, P., Hunter, M. S., Kassemeyer, S., Kimmel, N., Kirian, R., Maia, F. R. N. C., Marchesini, S., Martin, A. V., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schlichting, I., Schulz, J., Seibert, M. M., Sierra, R. G., Soltau, H., Starodub, D., Stellato, F., Stern, S., Strülder, L., Timneanu, N., Ullrich, J., Wahlgren, W. Y., Wang, X., Weidenspointner, G., Wunderer, C., Fromme, P., Chapman, H. N., Spence, J. & Neutze, R., Mar 2012, In : Nature Methods. 9, 3, p. 263-265 3 p.

Research output: Contribution to journalArticle

124 Scopus citations

Macromolecular diffractive imaging using imperfect crystals

Ayyer, K., Yefanov, O. M., Oberthür, D., Roy-Chowdhury, S., Galli, L., Mariani, V., Basu, S., Coe, J., Conrad, C. E., Fromme, R., Schaffer, A., Dörner, K., James, D., Kupitz, C., Metz, M., Nelson, G., Xavier, P. L., Beyerlein, K. R., Schmidt, M., Sarrou, I. & 14 others, Spence, J., Weierstall, U., White, T. A., Yang, J. H., Zhao, Y., Liang, M., Aquila, A., Hunter, M. S., Robinson, J. S., Koglin, J. E., Boutet, S., Fromme, P., Barty, A. & Chapman, H. N., Feb 10 2016, In : Nature. 530, 7589, p. 202-206 5 p.

Research output: Contribution to journalArticle

77 Scopus citations

Mapping the continuous reciprocal space intensity distribution of X-ray serial crystallography

Yefanov, O., Gati, C., Bourenkov, G., Kirian, R., White, T. A., Spence, J., Chapman, H. N. & Barty, A., Jul 17 2014, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1647, 20130333.

Research output: Contribution to journalArticle

23 Scopus citations

Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction

Abdallah, B. G., Zatsepin, N., Roy-Chowdhury, S., Coe, J., Conrad, C. E., Dörner, K., Sierra, R. G., Stevenson, H. P., Camacho-Alanis, F., Grant, T. D., Nelson, G., James, D., Calero, G., Wachter, R., Spence, J., Weierstall, U., Fromme, P. & Ros, A., Jul 1 2015, In : Structural Dynamics. 2, 4, 041719.

Research output: Contribution to journalArticle

12 Scopus citations

Natively inhibited trypanosoma brucei cathepsin B structure determined by using an x-ray laser

Redecke, L., Nass, K., DePonte, D. P., White, T. A., Rehders, D., Barty, A., Stellato, F., Liang, M., Barends, T. R. M., Boutet, S., Williams, G. J., Messerschmidt, M., Seibert, M. M., Aquila, A., Arnlund, D., Bajt, S., Barth, T. B., Bogan, M. J., Caleman, C., Chao, T. C. & 29 others, Doak, R. B., Fleckenstein, H., Frank, M., Fromme, R., Galli, L., Grotjohann, I., Hunter, M. S., Johansson, L. C., Kassemeyer, S., Katona, G., Kirian, R., Koopmann, R., Kupitz, C., Lomb, L., Martin, A. V., Mogk, S., Neutze, R., Shoeman, R. L., Steinbrener, J., Timneanu, N., Wang, D., Weierstall, U., Zatsepin, N., Spence, J., Fromme, P., Schlichting, I., Duszenko, M., Betzel, C. & Chapman, H. N., Jan 11 2013, In : Science. 339, 6116, p. 227-230 4 p.

Research output: Contribution to journalArticle

310 Scopus citations

Native phasing of x-ray free-electron laser data for a G protein–coupled receptor

Batyuk, A., Galli, L., Ishchenko, A., Han, G. W., Gati, C., Popov, P. A., Lee, M. Y., Stauch, B., White, T. A., Barty, A., Aquila, A., Hunter, M. S., Liang, M., Boutet, S., Pu, M., Liu, Z. J., Nelson, G., James, D., Li, C., Zhao, Y. & 7 others, Spence, J., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R. C. & Cherezov, V., Sep 2016, In : Science Advances. 2, 9, e1600292.

Research output: Contribution to journalArticle

57 Scopus citations

New directions in X-ray microscopy

Falcone, R., Jacobsen, C., Kirz, J., Marchesini, S., Shapiro, D. & Spence, J., Jul 1 2011, In : Contemporary Physics. 52, 4, p. 293-318 26 p.

Research output: Contribution to journalArticle

58 Scopus citations

New light on disordered ensembles: Ab initio structure determination of one particle from scattering fluctuations of many copies

Saldin, D. K., Poon, H. C., Bogan, M. J., Marchesini, S., Shapiro, D. A., Kirian, R., Weierstall, U. & Spence, J., Mar 14 2011, In : Physical Review Letters. 106, 11, 115501.

Research output: Contribution to journalArticle

61 Scopus citations

Ondrej Krivanek's early scientific research

Spence, J., Oct 2 2016, (Accepted/In press) In : Ultramicroscopy.

Research output: Contribution to journalArticle

On the dose-rate threshold of beam damage in TEM

Jiang, N. & Spence, J., Feb 1 2012, In : Ultramicroscopy. 113, p. 77-82 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

On the measurement of the Casimir torque

Chen, X. & Spence, J., Sep 2011, In : Physica Status Solidi (B) Basic Research. 248, 9, p. 2064-2071 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Phasing of coherent femtosecond X-ray diffraction from size-varying nanocrystals

Spence, J., Kirian, R., Wang, X., Weierstall, U., Schmidt, K., White, T., Barty, A., Chapman, H. N., Marchesini, S. & Holton, J., Feb 14 2011, In : Optics Express. 19, 4, p. 2866-2873 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

Radiation damage in protein serial femtosecond crystallography using an x-ray free-electron laser

Lomb, L., Barends, T. R. M., Kassemeyer, S., Aquila, A., Epp, S. W., Erk, B., Foucar, L., Hartmann, R., Rudek, B., Rolles, D., Rudenko, A., Shoeman, R. L., Andreasson, J., Bajt, S., Barthelmess, M., Barty, A., Bogan, M. J., Bostedt, C., Bozek, J. D., Caleman, C. & 45 others, Coffee, R., Coppola, N., Deponte, D. P., Doak, R. B., Ekeberg, T., Fleckenstein, H., Fromme, P., Gebhardt, M., Graafsma, H., Gumprecht, L., Hampton, C. Y., Hartmann, A., Hauser, G., Hirsemann, H., Holl, P., Holton, J. M., Hunter, M. S., Kabsch, W., Kimmel, N., Kirian, R., Liang, M., Maia, F. R. N. C., Meinhart, A., Marchesini, S., Martin, A. V., Nass, K., Reich, C., Schulz, J., Seibert, M. M., Sierra, R., Soltau, H., Spence, J., Steinbrener, J., Stellato, F., Stern, S., Timneanu, N., Wang, X., Weidenspointner, G., Weierstall, U., White, T. A., Wunderer, C., Chapman, H. N., Ullrich, J., Strüder, L. & Schlichting, I., Dec 20 2011, In : Physical Review B - Condensed Matter and Materials Physics. 84, 21, 214111.

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127 Scopus citations

Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements

Barty, A., Caleman, C., Aquila, A., Timneanu, N., Lomb, L., White, T. A., Andreasson, J., Arnlund, D., Bajt, S., Barends, T. R. M., Barthelmess, M., Bogan, M. J., Bostedt, C., Bozek, J. D., Coffee, R., Coppola, N., Davidsson, J., Deponte, D. P., Doak, R. B., Ekeberg, T. & 48 others, Elser, V., Epp, S. W., Erk, B., Fleckenstein, H., Foucar, L., Fromme, P., Graafsma, H., Gumprecht, L., Hajdu, J., Hampton, C. Y., Hartmann, R., Hartmann, A., Hauser, G., Hirsemann, H., Holl, P., Hunter, M. S., Johansson, L., Kassemeyer, S., Kimmel, N., Kirian, R., Liang, M., Maia, F. R. N. C., Malmerberg, E., Marchesini, S., Martin, A. V., Nass, K., Neutze, R., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Scott, H., Schlichting, I., Schulz, J., Marvin Seibert, M., Shoeman, R. L., Sierra, R. G., Soltau, H., Spence, J., Stellato, F., Stern, S., Strüder, L., Ullrich, J., Wang, X., Weidenspointner, G., Weierstall, U., Wunderer, C. B. & Chapman, H. N., Jan 2012, In : Nature Photonics. 6, 1, p. 35-40 6 p.

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248 Scopus citations

Serial femtosecond crystallography of G protein-coupled receptors

Liu, W., Wacker, D., Gati, C., Han, G. W., James, D., Wang, D., Nelson, G., Weierstall, U., Katritch, V., Barty, A., Zatsepin, N., Li, D., Messerschmidt, M., Boutet, S., Williams, G. J., Koglin, J. E., Seibert, M. M., Wang, C., Shah, S. T. A., Basu, S. & 13 others, Fromme, R., Kupitz, C., Rendek, K. N., Grotjohann, I., Fromme, P., Kirian, R., Beyerlein, K. R., White, T. A., Chapman, H. N., Caffrey, M., Spence, J., Stevens, R. C. & Cherezov, V., 2013, In : Science. 342, 6165, p. 1521-1524 4 p.

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312 Scopus citations

Serial femtosecond crystallography of soluble proteins in lipidic cubic phase

Fromme, R., Ishchenko, A., Metz, M., Chowdhury, S. R., Basu, S., Boutet, S., Fromme, P., White, T. A., Barty, A., Spence, J., Weierstall, U., Liu, W. & Cherezov, V., Sep 1 2015, In : IUCrJ. 2, p. 545-551 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Lawrence, R. M., Conrad, C. E., Zatsepin, N., Grant, T. D., Liu, H., James, D., Nelson, G., Subramanian, G., Aquila, A., Hunter, M. S., Liang, M., Boutet, S., Coe, J., Spence, J., Weierstall, U., Liu, W., Fromme, P., Cherezov, V. & Hogue, B., Jul 1 2015, In : Structural Dynamics. 2, 4, 041720.

Research output: Contribution to journalArticle

10 Scopus citations
47 Scopus citations

Simulations of radiation damage in biomolecular nanocrystals induced by femtosecond X-ray pulses

Caleman, C., Bergh, M., Scott, H. A., Spence, J., Chapman, H. N. & Timneanu, N., Sep 20 2011, In : Journal of Modern Optics. 58, 16, p. 1486-1497 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

Single mimivirus particles intercepted and imaged with an X-ray laser

Seibert, M. M., Ekeberg, T., Maia, F. R. N. C., Svenda, M., Andreasson, J., Jönsson, O., Odić, D., Iwan, B., Rocker, A., Westphal, D., Hantke, M., Deponte, D. P., Barty, A., Schulz, J., Gumprecht, L., Coppola, N., Aquila, A., Liang, M., White, T. A., Martin, A. & 69 others, Caleman, C., Stern, S., Abergel, C., Seltzer, V., Claverie, J. M., Bostedt, C., Bozek, J. D., Boutet, S., Miahnahri, A. A., Messerschmidt, M., Krzywinski, J., Williams, G., Hodgson, K. O., Bogan, M. J., Hampton, C. Y., Sierra, R. G., Starodub, D., Andersson, I., Bajt, S., Barthelmess, M., Spence, J., Fromme, P., Weierstall, U., Kirian, R., Hunter, M., Doak, R. B., Marchesini, S., Hau-Riege, S. P., Frank, M., Shoeman, R. L., Lomb, L., Epp, S. W., Hartmann, R., Rolles, D., Rudenko, A., Schmidt, C., Foucar, L., Kimmel, N., Holl, P., Rudek, B., Erk, B., Hömke, A., Reich, C., Pietschner, D., Weidenspointner, G., Strüder, L., Hauser, G., Gorke, H., Ullrich, J., Schlichting, I., Herrmann, S., Schaller, G., Schopper, F., Soltau, H., Kühnel, K. U., Andritschke, R., Schröter, C. D., Krasniqi, F., Bott, M., Schorb, S., Rupp, D., Adolph, M., Gorkhover, T., Hirsemann, H., Potdevin, G., Graafsma, H., Nilsson, B., Chapman, H. N. & Hajdu, J., Feb 3 2011, In : Nature. 470, 7332, p. 78-82 5 p.

Research output: Contribution to journalArticle

638 Scopus citations

Single-particle structure determination by correlations of snapshot X-ray diffraction patterns

Starodub, D., Aquila, A., Bajt, S., Barthelmess, M., Barty, A., Bostedt, C., Bozek, J. D., Coppola, N., Doak, R. B., Epp, S. W., Erk, B., Foucar, L., Gumprecht, L., Hampton, C. Y., Hartmann, A., Hartmann, R., Holl, P., Kassemeyer, S., Kimmel, N., Laksmono, H. & 24 others, Liang, M., Loh, N. D., Lomb, L., Martin, A. V., Nass, K., Reich, C., Rolles, D., Rudek, B., Rudenko, A., Schulz, J., Shoeman, R. L., Sierra, R. G., Soltau, H., Steinbrener, J., Stellato, F., Stern, S., Weidenspointner, G., Frank, M., Ullrich, J., Strüder, L., Schlichting, I., Chapman, H. N., Spence, J. & Bogan, M. J., 2012, In : Nature communications. 3, 1276.

Research output: Contribution to journalArticle

65 Scopus citations

Solving protein nanocrystals by cryo-EM diffraction: Multiple scattering artifacts

Subramanian, G., Basu, S., Liu, H., Zuo, J. M. & Spence, J., Jan 1 2015, In : Ultramicroscopy. 148, p. 87-93 7 p.

Research output: Contribution to journalArticle

24 Scopus citations