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  • George Pettit
2018

Antineoplastic Agents. 605. Isoquinstatins

Pettit, G., Melody, N. & Chapuis, J., Mar 23 2018, In : Journal of Natural Products. 81, 3, p. 451-457 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Antineoplastic Agents. 606. the Betulastatins

Pettit, G., Melody, N. & Chapuis, J., Mar 23 2018, In : Journal of Natural Products. 81, 3, p. 458-464 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Antineoplastic Agents. 603. Quinstatins: Exceptional Cancer Cell Growth Inhibitors

Pettit, G., Melody, N. & Chapuis, J., Mar 24 2017, In : Journal of Natural Products. 80, 3, p. 692-698 7 p.

Research output: Contribution to journalReview article

8 Scopus citations

Antineoplastic Agents. 604. the Path of Quinstatin Derivatives to Antibody Drug Conjugates

Pettit, G., Melody, N. & Chapuis, J., Jan 1 2017, In : Journal of Natural Products. 80, 9, p. 2447-2452 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Antineoplastic Agents. 585. Isolation of Bridelia ferruginea Anticancer Podophyllotoxins and Synthesis of 4-Aza-podophyllotoxin Structural Modifications

Pettit, G., Searcy, J. D., Tan, R., Cragg, G. M., Melody, N., Knight, J. C. & Chapuis, J., Mar 25 2016, In : Journal of Natural Products. 79, 3, p. 507-518 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Isolation and Structure of Cancer Cell Growth Inhibitory Tetracyclic Triterpenoids from the Zimbabwean Monadenium lugardae

Pettit, G., Ye, Q., Herald, D. L., Knight, J. C., Hogan, F., Melody, N., Mukku, V. J. R. V., Doubek, D. L. & Chapuis, J., Jun 24 2016, In : Journal of Natural Products. 79, 6, p. 1598-1603 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

Antineoplastic agents. 599. Total synthesis of dolastatin 16

Pettit, G., Smith, T. H., Arce, P. M., Flahive, E. J., Anderson, C. R., Chapuis, J., Xu, J-P., Groy, T. L., Belcher, P. E. & Macdonald, C. B., Mar 27 2015, In : Journal of Natural Products. 78, 3, p. 476-485 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Antineoplastic agents. 600. from the south pacific ocean to the silstatins

Pettit, G., Arce, P. M., Chapuis, J. & Macdonald, C. B., Mar 27 2015, In : Journal of Natural Products. 78, 3, p. 510-523 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Antineoplastic agents 596. Isolation and structure of chromomycin A5 from a Beaufort Sea microorganism

Pettit, G., Tan, R., Pettit, R., Doubek, D. L., Chapuis, J. & Weber, C. A., 2015, In : RSC Advances. 5, 12, p. 9116-9122 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Neristatin 1 Provides Critical Insight into Bryostatin 1 Structure-Function Relationships

Kedei, N., Kraft, M. B., Keck, G. E., Herald, C. L., Melody, N., Pettit, G. & Blumberg, P. M., Apr 24 2015, In : Journal of Natural Products. 78, 4, p. 896-900 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

The cephalostatins. 23. Conversion of hecogenin to a steroidal 1,6-dioxaspiro[5.5]nonane analogue for cephalostatin 11

Pettit, G., Moser, B. R., Herald, D. L., Knight, J. C., Chapuis, J. & Zheng, X., May 22 2015, In : Journal of Natural Products. 78, 5, p. 1067-1072 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

The Cephalostatins. 24. Isolation, Structure, and Cancer Cell Growth Inhibition of Cephalostatin 20

Pettit, G., Xu, J-P., Chapuis, J. & Melody, N., Jun 26 2015, In : Journal of Natural Products. 78, 6, p. 1446-1450 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Antineoplastic agents. 595. structural modifications of betulin and the X-ray crystal structure of an unusual betulin amine dimer1

Pettit, G., Melody, N., Hempenstall, F., Chapuis, J., Groy, T. L. & Williams, L., Apr 25 2014, In : Journal of Natural Products. 77, 4, p. 863-872 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
2013

Isolation and structures of axistatins 1-3 from the Republic of Palau marine sponge Agelas axifera Hentschel(1)

Pettit, G., Tang, Y., Zhang, Q., Bourne, G. T., Arm, C. A., Leet, J. E., Knight, J. C., Pettit, R., Chapuis, J., Doubek, D. L., Ward, F. J., Weber, C. & Hooper, J. N. A., Mar 22 2013, In : Journal of Natural Products. 76, 3, p. 420-424 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent

Hadimani, M. B., MacDonough, M. T., Ghatak, A., Strecker, T. E., Lopez, R., Sriram, M., Nguyen, B. L., Hall, J. J., Kessler, R. J., Shirali, A. R., Liu, L., Garner, C. M., Pettit, G., Hamel, E., Chaplin, D. J., Mason, R. P., Trawick, M. L. & Pinney, K. G., Sep 27 2013, In : Journal of Natural Products. 76, 9, p. 1668-1678 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
2012

Antineoplastic agents. 548. Synthesis of iodo- and diiodocombstatin phosphate prodrugs

Pettit, G., Rosenberg, H. J., Dixon, R., Knight, J. C., Hamel, E., Chapuis, J., Pettit, R., Hogan, F., Sumner, B., Ain, K. B. & Trickey-Platt, B., Mar 23 2012, In : Journal of Natural Products. 75, 3, p. 385-393 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Antineoplastic agents. 587. Isolation and structure of 3-epipancratistatin from Narcissus cv. Ice Follies(1)

Pettit, G., Tan, R., Bao, G. H., Melody, N., Doubek, D. L., Gao, S., Chapuis, J. & Williams, L., Apr 27 2012, In : Journal of Natural Products. 75, 4, p. 771-773 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

Preclinical efficacy of sodium narcistatin to reduce inflammation and joint destruction in rats with adjuvant-induced arthritis

Lubahn, C., Schaller, J. A., Shewmacker, E., Wood, C., Bellinger, D. L., Byron, D., Melody, N., Pettit, G. & Lorton, D., Dec 2012, In : Rheumatology International. 32, 12, p. 3751-3760 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

The Cephalostatins. 22. Synthesis of bis-steroidal pyrazine pyrones

Pettit, G., Moser, B. R., Mendonça, R. F., Knight, J. C. & Hogan, F., Jun 22 2012, In : Journal of Natural Products. 75, 6, p. 1063-1069 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2011

A chemifluorescent immunoassay for the determination of marinobufagenin in body fluids

Abi-Ghanem, D., Lai, X., Berghman, L. R., Horvat, D., Li, J., Romo, D., Uddin, M. N., Kamano, Y., Nogawa, T., Xu, J-P., Pettit, G. & Puschett, J. B., Jan 2011, In : Journal of Immunoassay and Immunochemistry. 32, 1, p. 31-46 16 p.

Research output: Contribution to journalArticle

7 Scopus citations

Antineoplastic agents. 590. X-ray crystal structure of dolastatin 16 and syntheses of the dolamethylleuine and dolaphenvaline units

Pettit, G., Smith, T. H., Xu, J-P., Herald, D. L., Flahive, E. J., Anderson, C. R., Belcher, P. E. & Knight, J. C., May 27 2011, In : Journal of Natural Products. 74, 5, p. 1003-1008 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Antineoplastic agents. 592. Highly effective cancer cell growth inhibitory structural modifications of dolastatin 10

Pettit, G., Hogan, F. & Toms, S., May 27 2011, In : Journal of Natural Products. 74, 5, p. 962-968 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Interactions of halichondrin B and eribulin with tubulin

Bai, R., Nguyen, T. L., Burnett, J. C., Atasoylu, O., Munro, M. H. G., Pettit, G., Smith, A. B., Gussio, R. & Hamel, E., Jun 27 2011, In : Journal of Chemical Information and Modeling. 51, 6, p. 1393-1404 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Regioselective synthesis of water-soluble monophosphate derivatives of combretastatin A-1

Tanpure, R. P., Nguyen, B. L., Strecker, T. E., Aguirre, S., Sharma, S., Chaplin, D. J., Siim, B. G., Hamel, E., Lippert, J. W., Pettit, G., Trawick, M. L. & Pinney, K. G., Jul 22 2011, In : Journal of Natural Products. 74, 7, p. 1568-1574 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

The cephalostatins. 21. Synthesis of bis-steroidal pyrazine rhamnosides (1)

Pettit, G., Mendonca, R. F., Knight, J. C. & Pettit, R., Sep 23 2011, In : Journal of Natural Products. 74, 9, p. 1922-1930 9 p.

Research output: Contribution to journalArticle

16 Scopus citations