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Primary Biliary Cirrhosis

Lindor, K. & Levy, C., 2012, Zakim and Boyer's Hepatology. Elsevier Inc., p. 738-753 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biliary Liver Cirrhosis
17 Citations (Scopus)

Primary biliary cirrhosis in adults

Momah, N. & Lindor, K., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 4, p. 427-433 7 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Ursodeoxycholic Acid
Cholestasis
Liver Cirrhosis
Liver Diseases

Primary sclerosing cholangitis: Providing a safe and effective treatment

Imam, M. H. & Lindor, K., Jun 2012, In : Expert Review of Gastroenterology and Hepatology. 6, 3, p. 255-257 3 p.

Research output: Contribution to journalArticle

Cholagogues and Choleretics
Ursodeoxycholic Acid
Sclerosing Cholangitis
End Stage Liver Disease
Docosahexaenoic Acids
40 Citations (Scopus)

Primary sclerosing cholangitis: Overview and update

Mendes, F. & Lindor, K., Nov 2010, In : Nature Reviews Gastroenterology and Hepatology. 7, 11, p. 611-619 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
End Stage Liver Disease
Cholangiocarcinoma
Immunologic Factors
Liver Transplantation
43 Citations (Scopus)

Primary sclerosing cholangitis: A review and update on therapeutic developments

Tabibian, J. H. & Lindor, K., Feb 2013, In : Expert Review of Gastroenterology and Hepatology. 7, 2, p. 103-114 12 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Clinical Trials
Therapeutics
Common Hepatic Duct
End Stage Liver Disease

Primary sclerosing cholangitis

Treeprasertsuk, S. & Lindor, K., Apr 16 2012, Textbook of Clinical Gastroenterology and Hepatology: Second Edition. Wiley-Blackwell, p. 573-579 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sclerosing Cholangitis
Liver Transplantation
Survival
Ursodeoxycholic Acid
Cholangiocarcinoma
264 Citations (Scopus)

Primary sclerosing cholangitis

Hirschfield, G. M., Karlsen, T. H., Lindor, K. & Adams, D. H., 2013, In : The Lancet. 382, 9904, p. 1587-1599 13 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Inflammatory Bowel Diseases
End Stage Liver Disease
Cholangitis
Biliary Liver Cirrhosis

Primary Sclerosing Cholangitis

Eaton, J. E., Talwalkar, J. A. & Lindor, K., Dec 2013, The Autoimmune Diseases: Fifth Edition. Elsevier Inc., p. 925-936 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sclerosing Cholangitis
Liver Transplantation
Fibrosis
Intrahepatic Bile Ducts
Extrahepatic Bile Ducts
4 Citations (Scopus)

Primary sclerosing cholangitis, part 1: Epidemiology, etiopathogenesis, clinical features, and treatment

Tabibian, J. H., Ali, A. H. & Lindor, K., May 1 2018, In : Gastroenterology and Hepatology. 14, 5, p. 293-304 12 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Epidemiology
Liver Transplantation
Therapeutics
End Stage Liver Disease
4 Citations (Scopus)

Primary sclerosing cholangitis, part 2: Cancer risk, prevention, and surveillance

Tabibian, J. H., Ali, A. H. & Lindor, K., Jul 1 2018, In : Gastroenterology and Hepatology. 14, 7, p. 427-432 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Neoplasms
Cholangiocarcinoma
Expert Testimony
Gallbladder
45 Citations (Scopus)

Primary sclerosing cholangitis and the microbiota: Current knowledge and perspectives on etiopathogenesis and emerging therapies

Tabibian, J. H., O'Hara, S. P. & Lindor, K., 2014, In : Scandinavian Journal of Gastroenterology. 49, 8, p. 901-908 8 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Microbiota
Inflammatory Bowel Diseases
Therapeutics
Enterohepatic Circulation
86 Citations (Scopus)

Primary sclerosing cholangitis associated with elevated immunoglobulinG4: Clinical characteristics and response to therapy

Björnsson, E., Chari, S., Silveira, M., Gossard, A., Takahashi, N., Smyrk, T. & Lindor, K., May 2011, In : American Journal of Therapeutics. 18, 3, p. 198-205 8 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Immunoglobulins
Therapeutics
Steroids
Pathologic Constriction

Primary sclerosing cholangitis in children versus adults: lessons for the clinic

Adike, A., Carey, E. J. & Lindor, K., Oct 3 2018, In : Expert Review of Gastroenterology and Hepatology. 12, 10, p. 1025-1032 8 p.

Research output: Contribution to journalReview article

Sclerosing Cholangitis
Pediatrics
Liver Diseases
Literature
Inflammatory Bowel Diseases
73 Citations (Scopus)

Primary sclerosing cholangitis patients with serial polysomy fluorescence in situ hybridization results are at increased risk of cholangiocarcinoma

Fritcher, E. G. B., Kipp, B. R., Voss, J. S., Clayton, A. C., Lindor, K., Halling, K. C. & Gores, G. J., Nov 2011, In : American Journal of Gastroenterology. 106, 11, p. 2023-2028 6 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Fluorescence In Situ Hybridization
Endoscopic Retrograde Cholangiopancreatography
Cell Biology
22 Citations (Scopus)

Prospective clinical trial of rifaximin therapy for patients with primary sclerosing cholangitis

Tabibian, J. H., Gossard, A., El-Youssef, M., Eaton, J. E., Petz, J., Jorgensen, R., Enders, F. B., Tabibian, A. & Lindor, K., Jun 9 2014, (Accepted/In press) In : American Journal of Therapeutics.

Research output: Contribution to journalArticle

rifaximin
Sclerosing Cholangitis
Clinical Trials
Alkaline Phosphatase
Liver Diseases
115 Citations (Scopus)

Randomised clinical trial: Vancomycin or metronidazole in patients with primary sclerosing cholangitis - A pilot study

Tabibian, J. H., Weeding, E., Jorgensen, R. A., Petz, J. L., Keach, J. C., Talwalkar, J. A. & Lindor, K., Mar 2013, In : Alimentary Pharmacology and Therapeutics. 37, 6, p. 604-612 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Metronidazole
Vancomycin
Randomized Controlled Trials
Alkaline Phosphatase
110 Citations (Scopus)

Recent advances in the development of farnesoid X receptor agonists

Ali, A. H., Carey, E. J. & Lindor, K., Jan 1 2015, In : Annals of Translational Medicine. 3, 1, 5.

Research output: Contribution to journalReview article

Bile Acids and Salts
Chenodeoxycholic Acid
Insulin Resistance
Biliary Liver Cirrhosis
Wounds and Injuries
1 Citation (Scopus)

Recent developments in the management of idiopathic cholestatic liver disease

Imam, M. H., Weeding, E. & Lindor, K., 2012, In : Annals of Gastroenterology. 25, 4, p. 317-326 10 p.

Research output: Contribution to journalArticle

Touch
Liver Diseases
Therapeutics

Recurrence of primary sclerosing cholangitis after liver transplantation

Charatcharoenwitthaya, P. & Lindor, K., Jan 1 2015, Disease Recurrence After Liver Transplantation: Natural History, Treatment and Survival. Springer New York, p. 121-134 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sclerosing Cholangitis
Liver Transplantation
Recurrence
Graft Survival
Fibrosis
47 Citations (Scopus)

Recurrent primary biliary cirrhosis after liver transplantation

Silveira, M. G., Talwalkar, J. A., Lindor, K. & Wiesner, R. H., Apr 2010, In : American Journal of Transplantation. 10, 4, p. 720-726 7 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Liver Transplantation
Ursodeoxycholic Acid
Graft Survival
Immunosuppression
17 Citations (Scopus)

Reliability and validity of the Chronic Liver Disease Questionnaire (CLDQ) in adults with non-alcoholic steatohepatitis (NASH)

Chawla, K. S., Talwalkar, J. A., Keach, J. C., Malinchoc, M., Lindor, K. & Jorgensen, R., Dec 31 2016, In : BMJ Open Gastroenterology. 3, 1, e000069.

Research output: Contribution to journalArticle

Fatty Liver
Reproducibility of Results
Liver Diseases
Chronic Disease
Quality of Life

Reply

Lindor, R. A. & Lindor, K., Aug 2011, In : Hepatology. 54, 2, p. 740 1 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Review article: the evidence that vancomycin is a therapeutic option for primary sclerosing cholangitis

Damman, J. L., Rodriguez, E. A., Ali, A. H., Buness, C. W., Cox, K. L., Carey, E. J. & Lindor, K., Apr 1 2018, In : Alimentary Pharmacology and Therapeutics. 47, 7, p. 886-895 10 p.

Research output: Contribution to journalReview article

Sclerosing Cholangitis
Vancomycin
Inflammatory Bowel Diseases
Therapeutics
Anti-Bacterial Agents
46 Citations (Scopus)

Role of the microbiota and antibiotics in primary sclerosing cholangitis

Tabibian, J. H., Talwalkar, J. A. & Lindor, K., 2013, In : BioMed Research International. 2013, 389537.

Research output: Contribution to journalArticle

Drug therapy
Sclerosing Cholangitis
Microbiota
Anti-Bacterial Agents
Liver
15 Citations (Scopus)

Secondary Sclerosing Cholangitis. Pathogenesis, Diagnosis, and Management.

Imam, M. H., Talwalkar, J. A. & Lindor, K., May 2013, In : Clinics in Liver Disease. 17, 2, p. 269-277 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Disease Management
Rare Diseases
Liver Transplantation
Acquired Immunodeficiency Syndrome
10 Citations (Scopus)

Serum lipids in primary sclerosing cholangitis

Sinakos, E., Abbas, G., Jorgensen, R. A. & Lindor, K., Jan 2012, In : Digestive and Liver Disease. 44, 1, p. 44-48 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Lipids
Serum
LDL Cholesterol
Ursodeoxycholic Acid
5 Citations (Scopus)

Shifting Paradigms: What Is the True Prevalence and Clinical Course of Primary Sclerosing Cholangitis?

Weersma, R. K. & Lindor, K., Oct 1 2016, In : Gastroenterology. 151, 4, p. 590-593 4 p.

Research output: Contribution to journalEditorial

Sclerosing Cholangitis
64 Citations (Scopus)

Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: A multicentre international study

Trivedi, P. J., Lammers, W. J., Van Buuren, H. R., Parés, A., Floreani, A., Janssen, H. L. A., Invernizzi, P., Battezzati, P. M., Ponsioen, C. Y., Corpechot, C., Poupon, R., Mayo, M. J., Burroughs, A. K., Nevens, F., Mason, A. L., Kowdley, K. V., Lleo, A., Caballeria, L., Lindor, K., Hansen, B. E. & 1 others, Hirschfield, G. M., Feb 1 2016, In : Gut. 65, 2, p. 321-329 9 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Multicenter Studies
Hepatocellular Carcinoma
Kaplan-Meier Estimate
North America
18 Citations (Scopus)

Surveillance for hepatobiliary cancers in patients with primary sclerosing cholangitis

Ali, A. H., Tabibian, J. H., Nasser-Ghodsi, N., Lennon, R. J., DeLeon, T., Borad, M. J., Hilscher, M., Silveira, M. G., Carey, E. J. & Lindor, K., Jun 1 2018, In : Hepatology. 67, 6, p. 2338-2351 14 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Cholangiocarcinoma
Neoplasms
Gallbladder
Survival

Targets and investigative treatments for primary biliary cholangitis

Ali, A. H., Carey, E. J. & Lindor, K., Oct 2 2016, In : Expert Opinion on Orphan Drugs. 4, 10, p. 1011-1020 10 p.

Research output: Contribution to journalReview article

Cholangitis
Ursodeoxycholic Acid
Therapeutics
Phase III Clinical Trials
Phase II Clinical Trials
80 Citations (Scopus)

The Framingham risk score and heart disease in nonalcoholic fatty liver disease

Treeprasertsuk, S., Leverage, S., Adams, L. A., Lindor, K., St Sauver, J. & Angulo, P., Jul 2012, In : Liver International. 32, 6, p. 945-950 6 p.

Research output: Contribution to journalArticle

Coronary Disease
Heart Diseases
Non-alcoholic Fatty Liver Disease
Longitudinal Studies
6 Citations (Scopus)

The management of autoimmunity in patients with cholestatic liver diseases

Ali, A. H., Carey, E. J. & Lindor, K., Jan 2 2016, (Accepted/In press) In : Expert Review of Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Autoimmunity
Liver Diseases
Autoimmune Diseases
Sclerosing Cholangitis
Cholangitis
5 Citations (Scopus)

The Microbiome and Primary Sclerosing Cholangitis

Ali, A. H., Carey, E. J. & Lindor, K., Sep 1 2016, In : Seminars in Liver Disease. 36, 4, p. 340-348 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Microbiota
End Stage Liver Disease
Probiotics
Ulcerative Colitis
23 Citations (Scopus)

The natural history of primary biliary cirrhosis

Imam, M. H. & Lindor, K., 2014, In : Seminars in Liver Disease. 34, 3, p. 329-333 5 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Ursodeoxycholic Acid
Touch
Early Diagnosis

The possible link between the thyroid and autoimmune liver diseases: Reply

Silveira, M. G. & Lindor, K., Sep 2010, In : Liver International. 30, 8, p. 1240-1241 2 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
Liver Diseases
Thyroid Gland
16 Citations (Scopus)

The predictors of the presence of varices in patients with primary sclerosing cholangitis

Treeprasertsuk, S., Kowdley, K. V., Luketic, V. A. C., Harrison, M. E., McCashland, T., Befeler, A. S., Harnois, D., Jorgensen, R., Petz, J., Keach, J., Schmoll, J., Hoskin, T., Thapa, P., Enders, F. & Lindor, K., Apr 2010, In : Hepatology. 51, 4, p. 1302-1310 9 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Varicose Veins
Platelet Count
Bilirubin
Endoscopy
25 Citations (Scopus)

The safety and efficacy of oral docosahexaenoic acid supplementation for the treatment of primary sclerosing cholangitis - A pilot study

Martin, C. R., Blanco, P. G., Keach, J. C., Petz, J. L., Zaman, M. M., Bhaskar, K. R., Cluette-Brown, J. E., Gautam, S., Sheth, S., Afdhal, N. H., Lindor, K. & Freedman, S. D., Jan 2012, In : Alimentary Pharmacology and Therapeutics. 35, 2, p. 255-265 11 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Docosahexaenoic Acids
Safety
Alkaline Phosphatase
Cystic Fibrosis Transmembrane Conductance Regulator
14 Citations (Scopus)

The spontaneous course of liver enzymes and its correlation in nonalcoholic fatty liver disease

Charatcharoenwitthaya, P., Lindor, K. & Angulo, P., Jul 2012, In : Digestive Diseases and Sciences. 57, 7, p. 1925-1931 7 p.

Research output: Contribution to journalArticle

Liver
Enzymes
Body Weight Changes
Transaminases
Non-alcoholic Fatty Liver Disease
156 Citations (Scopus)

The use of liver biopsy evaluation in discrimination of idiopathic autoimmune hepatitis versus drug-induced liver injury

Suzuki, A., Brunt, E. M., Kleiner, D. E., Miquel, R., Smyrk, T. C., Andrade, R. J., Isabel Lucena, M., Castiella, A., Lindor, K. & Björnsson, E., Sep 2 2011, In : Hepatology. 54, 3, p. 931-939 9 p.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Autoimmune Hepatitis
Biopsy
Liver
Cholestasis
11 Citations (Scopus)

The value of observational research in liver diseases

Lindor, R. A. & Lindor, K., Jan 2011, In : Hepatology. 53, 1, p. 1-3 3 p.

Research output: Contribution to journalArticle

Patient-Centered Care
Hepatitis C
Registries
Liver Diseases
Research Design
14 Citations (Scopus)

Treatment options for primary sclerosing cholangitis

Sinakos, E. & Lindor, K., Aug 2010, In : Expert Review of Gastroenterology and Hepatology. 4, 4, p. 473-488 16 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Ursodeoxycholic Acid
Liver Transplantation
Pathologic Constriction
Fibrosis
71 Citations (Scopus)

Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation

Risques, R. A., Lai, L. A., Himmetoglu, C., Ebaee, A., Li, L., Feng, Z., Bronner, M. P., Al-Lahham, B., Kowdley, K. V., Lindor, K., Rabinovitch, P. S. & Brentnall, T. A., Mar 1 2011, In : Cancer Research. 71, 5, p. 1669-1679 11 p.

Research output: Contribution to journalArticle

Telomere
Ulcerative Colitis
Colorectal Neoplasms
Inflammation
Telomere Shortening
37 Citations (Scopus)

Unmet clinical need in autoimmune liver diseases

Dyson, J. K., Webb, G., Hirschfield, G. M., Lohse, A., Beuers, U., Lindor, K. & Jones, D. E. J., Jan 1 2015, In : Journal of Hepatology. 62, 1, p. 208-218 11 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
Liver Diseases
Therapeutics
Research
23 Citations (Scopus)

Ursodeoxycholic acid in primary sclerosing cholangitis: If withdrawal is bad, then administration is good (right?)

Tabibian, J. H. & Lindor, K., 2014, In : Hepatology. 60, 3, p. 785-788 4 p.

Research output: Contribution to journalArticle

Cholagogues and Choleretics
Ursodeoxycholic Acid
Sclerosing Cholangitis
Bile Acids and Salts
4 Citations (Scopus)

Ursodeoxycholic acid therapy and liver transplant-free survival in patients with primary biliary cholangitis

Harms, M. H., van Buuren, H. R., Corpechot, C., Thorburn, D., Janssen, H. L. A., Lindor, K., Hirschfield, G. M., Parés, A., Floreani, A., Mayo, M. J., Invernizzi, P., Battezzati, P. M., Nevens, F., Ponsioen, C. Y., Mason, A. L., Kowdley, K. V., Lammers, W. J., Hansen, B. E. & van der Meer, A. J., Jan 1 2019, In : Journal of Hepatology.

Research output: Contribution to journalArticle

Ursodeoxycholic Acid
Cholangitis
Transplants
Survival
Liver

Ursodeoxycholic acid treatment in primary sclerosing cholangitis

Tabibian, J. H. & Lindor, K., Jan 1 2016, Primary Sclerosing Cholangitis: Current Understanding, Management, and Future Developments. Springer International Publishing, p. 145-152 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ursodeoxycholic Acid
Sclerosing Cholangitis
Liver Diseases
Clinical Trials
Drug Therapy
43 Citations (Scopus)

Ustekinumab for patients with primary biliary cholangitis who have an inadequate response to ursodeoxycholic acid: A proof-of-concept study

PURIFI Study Group, Jul 1 2016, In : Hepatology. 64, 1, p. 189-199 11 p.

Research output: Contribution to journalArticle

Ursodeoxycholic Acid
Cholangitis
Alkaline Phosphatase
Bile Acids and Salts
Liver Cirrhosis
25 Citations (Scopus)

Varices in early histological stage primary biliary cirrhosis

Ali, A. H., Sinakos, E., Silveira, M. G., Jorgensen, R. A., Angulo, P. & Lindor, K., Aug 2011, In : Journal of Clinical Gastroenterology. 45, 7

Research output: Contribution to journalArticle

Esophageal and Gastric Varices
Biliary Liver Cirrhosis
Varicose Veins
Bilirubin
Digestive System Endoscopy