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  • John Spence
2019

Diffractive imaging of single particles

Spence, J. C. H., Jan 1 2019, Springer Handbooks. Springer, p. 1009-1036 28 p. (Springer Handbooks).

Research output: Chapter in Book/Report/Conference proceedingChapter

High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source

Martin-Garcia, J. M., Zhu, L., Mendez, D., Lee, M. Y., Chun, E., Li, C., Hu, H., Subramanian, G., Kissick, D., Ogata, C., Henning, R., Ishchenko, A., Dobson, Z., Zhang, S., Weierstall, U., Spence, J. C. H., Fromme, P., Zatsepin, N., Fischetti, R. F., Cherezov, V. & 1 others, Liu, W., Jan 1 2019, In : IUCrJ. 6, p. 412-425 14 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Membrane protein megahertz crystallography at the European XFEL

Gisriel, C., Coe, J., Letrun, R., Yefanov, O. M., Luna-Chavez, C., Stander, N. E., Lisova, S., Mariani, V., Kuhn, M., Aplin, S., Grant, T. D., Dörner, K., Sato, T., Echelmeier, A., Cruz Villarreal, J., Hunter, M. S., Wiedorn, M. O., Knoska, J., Mazalova, V., Roy-Chowdhury, S. & 58 others, Yang, J. H., Jones, A., Bean, R., Bielecki, J., Kim, Y., Mills, G., Weinhausen, B., Meza, J. D., Al-Qudami, N., Bajt, S., Brehm, G., Botha, S., Boukhelef, D., Brockhauser, S., Bruce, B. D., Coleman, M. A., Danilevski, C., Discianno, E., Dobson, Z., Fangohr, H., Martin-Garcia, J. M., Gevorkov, Y., Hauf, S., Hosseinizadeh, A., Januschek, F., Ketawala, G. K., Kupitz, C., Maia, L., Manetti, M., Messerschmidt, M., Michelat, T., Mondal, J., Ourmazd, A., Previtali, G., Sarrou, I., Schön, S., Schwander, P., Shelby, M. L., Silenzi, A., Sztuk-Dambietz, J., Szuba, J., Turcato, M., White, T. A., Wrona, K., Xu, C., Abdellatif, M. H., Zook, J. D., Spence, J. C. H., Chapman, H. N., Barty, A., Kirian, R. A., Frank, M., Ros, A., Schmidt, M., Fromme, R., Mancuso, A. P., Fromme, P. & Zatsepin, N. A., Dec 1 2019, In : Nature communications. 10, 1, 5021.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Preface

Hawkes, P. W. & Spence, J. C. H., Jan 1 2019, In : Springer Handbooks. p. V-IX

Research output: Contribution to journalEditorial

Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome c oxidase

Ishigami, I., Lewis-Ballester, A., Echelmeier, A., Brehm, G., Zatsepin, N., Grant, T. D., Coe, J. D., Lisova, S., Nelson, G., Zhang, S., Dobson, Z. F., Boutet, S., Sierra, R. G., Batyuk, A., Fromme, P., Fromme, R., Spence, J. C. H., Ros, A., Yeh, S. R. & Rousseau, D. L., Feb 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3572-3577 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

SPIND: A reference-based auto-indexing algorithm for sparse serial crystallography data

Li, C., Li, X., Kirian, R., Spence, J., Liu, H. & Zatsepin, N., Jan 1 2019, In : IUCrJ. 6, p. 72-84 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018
4 Scopus citations

Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography

Olmos, J. L., Pandey, S., Martin-Garcia, J. M., Calvey, G., Katz, A., Knoska, J., Kupitz, C., Hunter, M. S., Liang, M., Oberthuer, D., Yefanov, O., Wiedorn, M., Heyman, M., Holl, M., Pande, K., Barty, A., Miller, M. D., Stern, S., Roy-Chowdhury, S., Coe, J. & 30 others, Nagaratnam, N., Zook, J., Verburgt, J., Norwood, T., Poudyal, I., Xu, D., Koglin, J., Seaberg, M. H., Zhao, Y., Bajt, S., Grant, T., Mariani, V., Nelson, G., Subramanian, G., Bae, E., Fromme, R., Fung, R., Schwander, P., Frank, M., White, T. A., Weierstall, U., Zatsepin, N., Spence, J., Fromme, P., Chapman, H. N., Pollack, L., Tremblay, L., Ourmazd, A., Phillips, G. N. & Schmidt, M., May 31 2018, In : BMC Biology. 16, 1, 59.

Research output: Contribution to journalArticle

37 Scopus citations

Erratum: Author Correction: Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography (Scientific reports (2018) 8 1 (2541))

Lee, D. B., Kim, J. M., Seok, J. H., Lee, J. H., Jo, J. D., Mun, J. Y., Conrad, C., Coe, J., Nelson, G., Hogue, B., White, T. A., Zatsepin, N., Weierstall, U., Barty, A., Chapman, H., Fromme, P., Spence, J., Chung, M. S., Oh, C. H. & Kim, K. H., Apr 17 2018, In : Scientific reports. 8, 1, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome

Woitowich, N. C., Halavaty, A. S., Waltz, P., Kupitz, C., Valera, J., Tracy, G., Gallagher, K. D., Claesson, E., Nakane, T., Pandey, S., Nelson, G., Tanaka, R., Nango, E., Mizohata, E., Owada, S., Tono, K., Joti, Y., Nugent, A. C., Patel, H., Mapara, A. & 21 others, Hopkins, J., Duong, P., Bizhga, D., Kovaleva, S. E., Peter, R. S., Hernandez, C. N., Ozarowski, W. B., Roy-Chowdhuri, S., Yang, J. H., Edlund, P., Takala, H., Ihalainen, J., Brayshaw, J., Norwood, T., Poudyal, I., Fromme, P., Spence, J., Moffat, K., Westenhoff, S., Schmidt, M. & Stojković, E. A., Jan 1 2018, In : IUCrJ. 5, p. 619-634 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography

Lee, D. B., Kim, J. M., Seok, J. H., Lee, J. H., Jo, J. D., Mun, J. Y., Conrad, C., Coe, J., Nelson, G., Hogue, B., White, T. A., Zatsepin, N., Weierstall, U., Barty, A., Chapman, H., Fromme, P., Spence, J., Chung, M. S., Oh, C. H. & Kim, K. H., Dec 1 2018, In : Scientific Reports. 8, 1, 2541.

Research output: Contribution to journalArticle

3 Scopus citations

The phase problem for two-dimensional crystals.II. Simulations

Arnal, R. D., Zhao, Y., Mitra, A. K., Spence, J. & Millane, R. P., Sep 1 2018, In : Acta Crystallographica Section A: Foundations and Advances. 74, 5, p. 537-544 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

X-ray lasers for structure and dynamics in biology

Spence, J., Jan 1 2018, In : IUCrJ. 5, p. 236-237 2 p.

Research output: Contribution to journalEditorial

4 Scopus citations
2017

Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser

Gati, C., Oberthuer, D., Yefanov, O., Bunker, R. D., Stellato, F., Chiu, E., Yeh, S. M., Aquila, A., Basu, S., Bean, R., Beyerlein, K. R., Botha, S., Boutet, S., DePonte, D. P., Doak, R. B., Fromme, R., Galli, L., Grotjohann, I., James, D. R., Kupitz, C. & 17 others, Lomb, L., Messerschmidt, M., Nass, K., Rendek, K., Shoeman, R. L., Wang, D., Weierstall, U., White, T. A., Williams, G. J., Zatsepin, N., Fromme, P., Spence, J., Goldie, K. N., Jehle, J. A., Metcalf, P., Barty, A. & Chapman, H. N., Feb 28 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 9, p. 2247-2252 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

CHAPTER 2: Imaging Protein Dynamics by XFELs

Spence, J., Jan 1 2017, Thermoelectric Materials and Devices. Bergmann, U., Yachandra, V. K. & Yano, J. (eds.). 18 ed. Royal Society of Chemistry, p. 47-69 23 p. (RSC Energy and Environment Series; vol. 2017-January, no. 18).

Research output: Chapter in Book/Report/Conference proceedingChapter

Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source

Reddy, H. K. N., Yoon, C. H., Aquila, A., Awel, S., Ayyer, K., Barty, A., Berntsen, P., Bielecki, J., Bobkov, S., Bucher, M., Carini, G. A., Carron, S., Chapman, H., Daurer, B., Demirci, H., Ekeberg, T., Fromme, P., Hajdu, J., Hanke, M. F., Hart, P. & 25 others, Hogue, B., Hosseinizadeh, A., Kim, Y., Kirian, R., Kurta, R. P., Larsson, D. S. D., Duane Loh, N., Maia, F. R. N. C., Mancuso, A. P., Mühlig, K., Munke, A., Nam, D., Nettelblad, C., Ourmazd, A., Rose, M., Schwander, P., Seibert, M., Sellberg, J. A., Song, C., Spence, J., Svenda, M., Van Der Schot, G., Vartanyants, I. A., Williams, G. J. & Lourdu Xavier, P., Jun 27 2017, In : Scientific Data. 4, 170079.

Research output: Contribution to journalArticle

23 Scopus citations

Corrigendum: Diffraction data of core-shell nanoparticles from an X-ray free electron laser

Li, X., Chiu, C. Y., Wang, H. J., Kassemeyer, S., Botha, S., Shoeman, R. L., Lawrence, R. M., Kupitz, C., Kirian, R., James, D., Wang, D., Nelson, G., Messerschmidt, M., Boutet, S., Williams, G. J., Hartmann, E., Jafarpour, A., Foucar, L. M., Barty, A., Chapman, H. & 13 others, Liang, M., Menzel, A., Wang, F., Basu, S., Fromme, R., Doak, R. B., Fromme, P., Weierstall, U., Huang, M. H., Spence, J. C. H., Schlichting, I., Hogue, B. G. & Liu, H., Oct 24 2017, In : Scientific Data. 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography

Oberthuer, D., Knoška, J., Wiedorn, M. O., Beyerlein, K. R., Bushnell, D. A., Kovaleva, E. G., Heymann, M., Gumprecht, L., Kirian, R. A., Barty, A., Mariani, V., Tolstikova, A., Adriano, L., Awel, S., Barthelmess, M., Dörner, K., Xavier, P. L., Yefanov, O., James, D. R., Nelson, G. & 25 others, Wang, D., Calvey, G., Chen, Y., Schmidt, A., Szczepek, M., Frielingsdorf, S., Lenz, O., Snell, E., Robinson, P. J., Šarler, B., Belšak, G., Maček, M., Wilde, F., Aquila, A., Boutet, S., Liang, M., Hunter, M. S., Scheerer, P., Lipscomb, J. D., Weierstall, U., Kornberg, R. D., Spence, J. C. H., Pollack, L., Chapman, H. N. & Bajt, S., Jun 21 2017, In : Scientific reports. 7, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Diffraction data of core-shell nanoparticles from an X-ray free electron laser

Li, X., Chiu, C. Y., Wang, H. J., Kassemeyer, S., Botha, S., Shoeman, R. L., Lawrence, R. M., Kupitz, C., Kirian, R., James, D., Wang, DI., Nelson, G., Messerschmidt, M., Boutet, S., Williams, G. J., Hartmann, E., Jafarpour, A., Foucar, L. M., Barty, A., Chapman, H. & 13 others, Liang, M., Menzel, A., Wang, F., Basu, S., Fromme, R., Doak, R. B., Fromme, P., Weierstall, U., Huang, M. H., Spence, J., Schlichting, I., Hogue, B. & Liu, H., Apr 11 2017, In : Scientific data. 4, 170048.

Research output: Contribution to journalArticle

3 Scopus citations

Double-flow focused liquid injector for efficient serial femtosecond crystallography

Oberthuer, D., Knoška, J., Wiedorn, M. O., Beyerlein, K. R., Bushnell, D. A., Kovaleva, E. G., Heymann, M., Gumprecht, L., Kirian, R., Barty, A., Mariani, V., Tolstikova, A., Adriano, L., Awel, S., Barthelmess, M., Dörner, K., Xavier, P. L., Yefanov, O., James, D. R., Nelson, G. & 25 others, Wang, D., Calvey, G., Chen, Y., Schmidt, A., Szczepek, M., Frielingsdorf, S., Lenz, O., Snell, E., Robinson, P. J., Šarler, B., Belšak, G., Maček, M., Wilde, F., Aquila, A., Boutet, S., Liang, M., Hunter, M. S., Scheerer, P., Lipscomb, J. D., Weierstall, U., Kornberg, R. D., Spence, J., Pollack, L., Chapman, H. N. & Bajt, S., Mar 16 2017, In : Scientific reports. 7, 44628.

Research output: Contribution to journalArticle

44 Scopus citations

Local electric field direct writing – Electron-beam lithography and mechanism

Jiang, N., Su, D. & Spence, J., Oct 5 2017, In : Microelectronic Engineering. 182, p. 8-14 7 p.

Research output: Contribution to journalArticle

Merging single-shot XFEL diffraction data from inorganic nanoparticles: A new approach to size and orientation determination

Li, X., Spence, J., Hogue, B. & Liu, H., Jan 1 2017, In : IUCrJ. 4, p. 741-750 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Outrunning damage: Electrons vs X-rays-timescales and mechanisms

Spence, J., Jul 1 2017, In : Structural Dynamics. 4, 4, 044027.

Research output: Contribution to journalArticle

22 Scopus citations

Serial crystallography at synchrotrons and X-ray lasers

Standfuss, J. & Spence, J., 2017, In : IUCrJ. 4, p. 100-101 2 p.

Research output: Contribution to journalEditorial

19 Scopus citations

Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation

Martin-Garcia, J. M., Conrad, C. E., Nelson, G., Stander, N., Zatsepin, N., Zook, J., Zhu, L., Geiger, J., Chun, E., Kissick, D., Hilgart, M. C., Ogata, C., Ishchenko, A., Nagaratnam, N., Roy-Chowdhury, S., Coe, J., Subramanian, G., Schaffer, A., James, D., Ketwala, G. & 10 others, Venugopalan, N., Xu, S., Corcoran, S., Ferguson, D., Weierstall, U., Spence, J., Cherezov, V., Fromme, P., Fischetti, R. F. & Liu, W., 2017, In : IUCrJ. 4, p. 439-454 16 p.

Research output: Contribution to journalArticle

47 Scopus citations

Short-wavelength free-electron laser sources and science: A review

Seddon, E. A., Clarke, J. A., Dunning, D. J., Masciovecchio, C., Milne, C. J., Parmigiani, F., Rugg, D., Spence, J., Thompson, N. R., Ueda, K., Vinko, S. M., Wark, J. S. & Wurth, W., Oct 23 2017, In : Reports on Progress in Physics. 80, 11, 115901.

Research output: Contribution to journalReview article

43 Scopus citations

Split-Second Reactions

Fromme, P. & Spence, J. C. H., Apr 18 2017, In : Scientific American. 316, 5, p. 62-67 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Structural enzymology using X-ray free electron lasers

Kupitz, C., Olmos, J. L., Holl, M., Tremblay, L., Pande, K., Pandey, S., Oberthür, D., Hunter, M., Liang, M., Aquila, A., Tenboer, J., Calvey, G., Katz, A., Chen, Y., Wiedorn, M. O., Knoska, J., Meents, A., Majriani, V., Norwood, T., Poudyal, I. & 30 others, Grant, T., Miller, M. D., Xu, W., Tolstikova, A., Morgan, A., Metz, M., Martin-Gracia, J., Zook, J. D., Roy-Chowdhury, S., Coe, J., Nagaratnam, N., Meza, D., Fromme, R., Basu, S., Frank, M., White, T., Barty, A., Bajt, S., Yefanov, O., Chapman, H. N., Zatsepin, N., Nelson, G., Weierstall, U., Spence, J., Schwander, P., Pollack, L., Fromme, P., Ourmazd, A., Phillips, G. N. & Schmidt, M., Jul 1 2017, In : Structural Dynamics. 4, 4, 044003.

Research output: Contribution to journalArticle

42 Scopus citations

Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

Stagno, J. R., Liu, Y., Bhandari, Y. R., Conrad, C. E., Panja, S., Swain, M., Fan, L., Nelson, G., Li, C., Wendel, D. R., White, T. A., Coe, J. D., Wiedorn, M. O., Knoska, J., Oberthuer, D., Tuckey, R. A., Yu, P., Dyba, M., Tarasov, S. G., Weierstall, U. & 18 others, Grant, T. D., Schwieters, C. D., Zhang, J., Ferré-D'Amaré, A. R., Fromme, P., Draper, D. E., Liang, M., Hunter, M. S., Boutet, S., Tan, K., Zuo, X., Ji, X., Barty, A., Zatsepin, N., Chapman, H. N., Spence, J., Woodson, S. A. & Wang, Y. X., Jan 12 2017, In : Nature. 541, 7636, p. 242-246 5 p.

Research output: Contribution to journalArticle

95 Scopus citations

XFELs for structure and dynamics in biology

Spence, J., Jan 1 2017, In : IUCrJ. 4, p. 322-339 18 p.

Research output: Contribution to journalArticle

57 Scopus citations

X-Ray Lasers in Biology Structure and Dynamics

Spence, J., 2017, Advances in Imaging and Electron Physics. Academic Press Inc., Vol. 200. p. 103-152 50 p. (Advances in Imaging and Electron Physics; vol. 200).

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations
2016

Advanced transmission electron microscopy: Imaging and diffraction in nanoscience

Zuo, J. M. & Spence, J., Jan 1 2016, Springer New York. 729 p.

Research output: Book/ReportBook

22 Scopus citations

Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein

Pande, K., Hutchison, C. D. M., Groenhof, G., Aquila, A., Robinson, J. S., Tenboer, J., Basu, S., Boutet, S., DePonte, D. P., Liang, M., White, T. A., Zatsepin, N., Yefanov, O., Morozov, D., Oberthuer, D., Gati, C., Subramanian, G., James, D., Zhao, Y., Koralek, J. & 24 others, Brayshaw, J., Kupitz, C., Conrad, C., Roy-Chowdhury, S., Coe, J. D., Metz, M., Xavier, P. L., Grant, T. D., Koglin, J. E., Ketawala, G., Fromme, R., Srajer, V., Henning, R., Spence, J., Ourmazd, A., Schwander, P., Weierstall, U., Frank, M., Fromme, P., Barty, A., Chapman, H. N., Moffat, K., Van Thor, J. J. & Schmidt, M., May 6 2016, In : Science. 352, 6286, p. 725-729 5 p.

Research output: Contribution to journalArticle

189 Scopus citations

Imaging enzyme kinetics at atomic resolution

Spence, J. & Lattman, E., 2016, In : IUCrJ. 3, p. 228-229 2 p.

Research output: Contribution to journalComment/debate

7 Scopus citations

Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography

Nogly, P., Panneels, V., Nelson, G., Gati, C., Kimura, T., Milne, C., Milathianaki, D., Kubo, M., Wu, W., Conrad, C., Coe, J., Bean, R., Zhao, Y., Båth, P., Dods, R., Harimoorthy, R., Beyerlein, K. R., Rheinberger, J., James, D., DePonte, D. & 20 others, Li, C., Sala, L., Williams, G. J., Hunter, M. S., Koglin, J. E., Berntsen, P., Nango, E., Iwata, S., Chapman, H. N., Fromme, P., Frank, M., Abela, R., Boutet, S., Barty, A., White, T. A., Weierstall, U., Spence, J., Neutze, R., Schertler, G. & Standfuss, J., Aug 22 2016, In : Nature communications. 7, 12314.

Research output: Contribution to journalArticle

44 Scopus citations

Macromolecular diffractive imaging using imperfect crystals

Ayyer, K., Yefanov, O. M., Oberthür, D., Roy-Chowdhury, S., Galli, L., Mariani, V., Basu, S., Coe, J., Conrad, C. E., Fromme, R., Schaffer, A., Dörner, K., James, D., Kupitz, C., Metz, M., Nelson, G., Xavier, P. L., Beyerlein, K. R., Schmidt, M., Sarrou, I. & 14 others, Spence, J., Weierstall, U., White, T. A., Yang, J. H., Zhao, Y., Liang, M., Aquila, A., Hunter, M. S., Robinson, J. S., Koglin, J. E., Boutet, S., Fromme, P., Barty, A. & Chapman, H. N., Feb 10 2016, In : Nature. 530, 7589, p. 202-206 5 p.

Research output: Contribution to journalArticle

73 Scopus citations

Measurements of transmitted electron beam extinction through Si crystal membranes

Nanni, E. A., Li, R. K., Limborg, C., Shen, X., Weathersby, S., Graves, W., Kirian, R., Spence, J. & Weierstall, U., 2016, IPAC 2016 - Proceedings of the 7th International Particle Accelerator Conference. Joint Accelerator Conferences Website (JACoW), p. 1611-1614 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Native phasing of x-ray free-electron laser data for a G protein–coupled receptor

Batyuk, A., Galli, L., Ishchenko, A., Han, G. W., Gati, C., Popov, P. A., Lee, M. Y., Stauch, B., White, T. A., Barty, A., Aquila, A., Hunter, M. S., Liang, M., Boutet, S., Pu, M., Liu, Z. J., Nelson, G., James, D., Li, C., Zhao, Y. & 7 others, Spence, J., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R. C. & Cherezov, V., Sep 1 2016, In : Science advances. 2, 9, e1600292.

Research output: Contribution to journalArticle

51 Scopus citations

Ondrej Krivanek's early scientific research

Spence, J., Oct 2 2016, (Accepted/In press) In : Ultramicroscopy.

Research output: Contribution to journalArticle

The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography

Edlund, P., Takala, H., Claesson, E., Henry, L., Dods, R., Lehtivuori, H., Panman, M., Pande, K., White, T., Nakane, T., Berntsson, O., Gustavsson, E., Båth, P., Modi, V., Roy-Chowdhury, S., Zook, J., Berntsen, P., Pandey, S., Poudyal, I., Tenboer, J. & 16 others, Kupitz, C., Barty, A., Fromme, P., Koralek, J. D., Tanaka, T., Spence, J., Liang, M., Hunter, M. S., Boutet, S., Nango, E., Moffat, K., Groenhof, G., Ihalainen, J., Stojkovi, E. A., Schmidt, M. & Westenhoff, S., Oct 19 2016, In : Scientific Reports. 6, 35279.

Research output: Contribution to journalArticle

22 Scopus citations

Three-dimensional-printed gas dynamic virtual nozzles for x-ray laser sample delivery

Nelson, G., Kirian, R., Weierstall, U., Zatsepin, N., Faragó, T., Baumbach, T., Wilde, F., Niesler, F. B. P., Zimmer, B., Ishigami, I., Hikita, M., Bajt, S., Yeh, S. R., Rousseau, D. L., Chapman, H. N., Spence, J. & Heymann, M., May 30 2016, In : Optics Express. 24, 11, p. 11515-11530 16 p.

Research output: Contribution to journalArticle

34 Scopus citations

XFEL data analysis for structural biology

Liu, H. & Spence, J., Sep 1 2016, In : Quantitative Biology. 4, 3, p. 159-176 18 p.

Research output: Contribution to journalReview article

11 Scopus citations

X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex

Zhou, X. E., Gao, X., Barty, A., Kang, Y., He, Y., Liu, W., Ishchenko, A., White, T. A., Yefanov, O., Han, G. W., Xu, Q., De Waal, P. W., Suino-Powell, K. M., Boutet, S., Williams, G. J., Wang, M., Li, D., Caffrey, M., Chapman, H. N., Spence, J. & 6 others, Fromme, P., Weierstall, U., Stevens, R. C., Cherezov, V., Melcher, K. & Xu, H. E., Apr 12 2016, In : Scientific Data. 3, 201621.

Research output: Contribution to journalArticle

25 Scopus citations
2015

A novel inert crystal delivery medium for serial femtosecond crystallography

Conrad, C. E., Basu, S., James, D., Wang, D., Schaffer, A., Roy-Chowdhury, S., Zatsepin, N., Aquila, A., Coe, J., Gati, C., Hunter, M. S., Koglin, J. E., Kupitz, C., Nelson, G., Subramanian, G., White, T. A., Zhao, Y., Zook, J., Boutet, S., Cherezov, V. & 4 others, Spence, J., Fromme, R., Weierstall, U. & Fromme, P., Jul 1 2015, In : IUCrJ. 2, p. 421-430 10 p.

Research output: Contribution to journalArticle

72 Scopus citations

Biphasic droplet-based sample delivery of protein crystals for serial femtosecond crystallography with an x-ray free electron laser

Echelmeier, A., Nelson, G., Abdallah, B. G., James, D., Roy-Chowdhury, S., Tolstikova, A., Mariani, V., Kirian, R., Oberthüer, D., Dörner, K., Fromme, P., Chapman, H. N., Weierstall, U., Spence, J. & Ros, A., 2015, MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, p. 1374-1376 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Kang, Y., Zhou, X. E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., White, T. A., Yefanov, O., Han, G. W., Xu, Q., De Waal, P. W., Ke, J., Tan, M. H. E., Zhang, C., Moeller, A., West, G. M., Pascal, B. D., Van Eps, N., Caro, L. N. & 52 others, Vishnivetskiy, S. A., Lee, R. J., Suino-Powell, K. M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G. J., Messerschmidt, M., Gati, C., Zatsepin, N., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C. E., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C. S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H. N., Spence, J., Fromme, P., Weierstall, U., Ernst, O. P., Katritch, V., Gurevich, V. V., Griffin, P. R., Hubbell, W. L., Stevens, R. C., Cherezov, V., Melcher, K. & Xu, H. E., Jul 30 2015, In : Nature. 523, 7562, p. 561-567 7 p.

Research output: Contribution to journalArticle

404 Scopus citations

Data collection strategies for time-resolved X-ray free-electron laser diffraction, and 2-color methods

Li, C., Schmidt, K. & Spence, J., Jul 1 2015, In : Structural Dynamics. 2, 4, 041714.

Research output: Contribution to journalArticle

7 Scopus citations

Electronic damage in S atoms in a native protein crystal induced by an intense X-ray free-electron laser pulse

Galli, L., Son, S. K., Klinge, M., Bajt, S., Barty, A., Bean, R., Betzel, C., Beyerlein, K. R., Caleman, C., Doak, R. B., Duszenko, M., Fleckenstein, H., Gati, C., Hunt, B., Kirian, R., Liang, M., Nanao, M. H., Nass, K., Oberthür, D., Redecke, L. & 7 others, Shoeman, R., Stellato, F., Yoon, C. H., White, T. A., Yefanov, O., Spence, J. & Chapman, H. N., Jul 1 2015, In : Structural Dynamics. 2, 4, 041703.

Research output: Contribution to journalArticle

10 Scopus citations

Hollow cone illumination for fast TEM, and outrunning damage with electrons

Spence, J., Subramanian, G. & Musumeci, P., Sep 23 2015, In : Journal of Physics B: Atomic, Molecular and Optical Physics. 48, 21, 214003.

Research output: Contribution to journalArticle

11 Scopus citations

Image reconstruction in serial femtosecond nanocrystallography using x-ray free-electron lasers

Chen, J. P. J., Kirian, R., Beyerlein, K. R., Bean, R. J., Morgan, A. J., Yefanov, O. M., Arnal, R. D., Wojtas, D. H., Bones, P. J., Chapman, H. N., Spence, J. & Millane, R. P., 2015, Proceedings of SPIE - The International Society for Optical Engineering. SPIE, Vol. 9600. 960002

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations