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  • Douglas McFadden
2016

Tanapox virus

Barrett, J. W. & McFadden, D., Apr 19 2016, Molecular Detection of Human Viral Pathogens. CRC Press, p. 1039-1046 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2020

Genome characterization of cetaceanpox virus from a managed Indo-Pacific bottlenose dolphin (Tursiops aduncus)

Rodrigues, T. C. S., Subramaniam, K., Varsani, A., McFadden, G., Schaefer, A. M., Bossart, G. D., Romero, C. H. & Waltzek, T. B., Mar 2020, In : Virus research. 278, 197861.

Research output: Contribution to journalArticle

2016

Therapeutics for graft-versus-host disease: From conventional therapies to novel virotherapeutic strategies

Villa, N. Y., Rahman, M. M., McFadden, G. & Cogle, C. R., Mar 2016, In : Viruses. 8, 3, 85.

Research output: Contribution to journalReview article

4 Scopus citations
2019

Quantifying Antibody Responses Induced by Antigen-Agnostic Immunotherapies

van Vloten, J. P., Klafuric, E. M., Karimi, K., McFadden, G., Petrik, J. J., Wootton, S. K. & Bridle, B. W., Sep 13 2019, In : Molecular Therapy - Methods and Clinical Development. 14, p. 189-196 8 p.

Research output: Contribution to journalArticle

Open Access
2017

Ex Vivo Oncolytic Virotherapy with Myxoma Virus Arms Multiple Allogeneic Bone Marrow Transplant Leukocytes to Enhance Graft versus Tumor

Lilly, C. L., Villa, N., Lemos de Matos, A., Ali, H. M., Dhillon, J. K. S., Hofland, T., Rahman, M., Chan, W., Bogen, B., Cogle, C. & McFadden, D., Mar 1 2017, In : Molecular Therapy - Oncolytics. 4, p. 31-40 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2016

M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of glioblastoma

Pisklakova, A., McKenzie, B., Zemp, F., Lun, X., Kenchappa, R. S., Etame, A. B., Rahman, M. M., Reilly, K., Pilon-Thomas, S., McFadden, G., Kurz, E. & Forsyth, P. A., Aug 1 2016, In : Neuro-Oncology. 18, 8, p. 1088-1098 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2019

Myxoma virus M013 protein antagonizes NF-κB and inflammasome pathways via distinct structural motifs

Garg, R. R., Jackson, C. B., Rahman, M. M., Khan, A. R., Lewin, A. S. & McFadden, G., May 24 2019, In : Journal of Biological Chemistry. 294, 21, p. 8480-8489 10 p.

Research output: Contribution to journalArticle

2018

Serpins: Development for therapeutic applications

Lucas, A., Yaron, J. R., Zhang, L., Macaulay, C. & McFadden, D., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 255-265 11 p. (Methods in Molecular Biology; vol. 1826).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
2019

Oncolytic virotherapy for small-cell lung cancer induces immune infiltration and prolongs survival

Kellish, P., Shabashvili, D., Rahman, M. M., Nawab, A., Guijarro, M. V., Zhang, M., Cao, C., Moussatche, N., Boyle, T., Antonia, S., Reinhard, M., Hartzell, C., Jantz, M., Mehta, H. J., McFadden, G., Kaye, F. J. & Zajac-Kaye, M., Jun 3 2019, In : Journal of Clinical Investigation. 129, 6, p. 2279-2292 14 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2016

Vaccinia virus dissemination requires p21-activated kinase 1

Andrade, L. G., Albarnaz, J. D., Mügge, F. L. B., David, B. A., Abrahão, J. S., da Fonseca, F. G., Kroon, E. G., Menezes, G. B., McFadden, D. & Bonjardim, C. A., Nov 1 2016, In : Archives of Virology. 161, 11, p. 2991-3002 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Poxvirus oncolytic virotherapy

Torres-Domínguez, L. E. & McFadden, G., Jun 3 2019, In : Expert Opinion on Biological Therapy. 19, 6, p. 561-573 13 p.

Research output: Contribution to journalReview article

5 Scopus citations
2016

Ex vivo virotherapy with myxoma virus does not impair hematopoietic stem and progenitor cells

Villa, N., Bais, S., Chan, W. M., Meacham, A. M., Wise, E., Rahman, M., Moreb, J. S., Rosenau, E. H., Wingard, J. R., McFadden, D. & Cogle, C. R., Mar 1 2016, In : Cytotherapy. 18, 3, p. 465-480 16 p.

Research output: Contribution to journalArticle

11 Scopus citations
2019

Author Correction: The wide utility of rabbits as models of human diseases (Experimental & Molecular Medicine, (2018), 50, 5, (66), 10.1038/s12276-018-0094-1)

Esteves, P. J., Abrantes, J., Baldauf, H. M., BenMohamed, L., Chen, Y., Christensen, N., González-Gallego, J., Giacani, L., Hu, J., Kaplan, G., Keppler, O. T., Knight, K. L., Kong, X. P., Lanning, D. K., Le Pendu, J., de Matos, A. L., Liu, J., Liu, S., Lopes, A. M., Lu, S. & 17 others, Lukehart, S., Manabe, Y. C., Neves, F., McFadden, G., Pan, R., Peng, X., de Sousa-Pereira, P., Pinheiro, A., Rahman, M., Ruvoën-Clouet, N., Subbian, S., Tuñón, M. J., van der Loo, W., Vaine, M., Via, L. E., Wang, S. & Mage, R., Jul 1 2019, In : Experimental and Molecular Medicine. 51, 7, 71.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Genetic characterization of a recombinant myxoma virus in the iberian hare (Lepus granatensis)

Águeda-Pinto, A., Matos, A. L. D., Abrantes, M., Kraberger, S., Risalde, M. A., Gortázar, C., McFadden, G., Varsani, A. & Esteves, P. J., Jun 2019, In : Viruses. 11, 6, 530.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2020
Open Access

Coinfections of novel polyomavirus, anelloviruses and a recombinant strain of myxoma virus-MYXV-tol identified in Iberian hares

Ägueda-Pinto, A., Kraberger, S., Lund, M. C., Gortázar, C., McFadden, G., Varsani, A. & Esteves, P. J., Jan 1 2020, In : Viruses. 12, 3, 340.

Research output: Contribution to journalArticle

Open Access
2018

Virotherapy as Potential Adjunct Therapy for Graft-Vs-Host Disease

Villa, N. & McFadden, D., Dec 1 2018, In : Current Pathobiology Reports. 6, 4, p. 247-263 17 p.

Research output: Contribution to journalReview article

Open Access
2019

Modifying the Organ Matrix Pre-engraftment: A New Transplant Paradigm?

Yaron, J. R., Kwiecien, J. M., Zhang, L., Ambadapadi, S., Wakefield, D. N., Clapp, W. L., Dabrowski, W., Burgin, M., Munk, B. H., McFadden, G., Chen, H. & Lucas, A. R., Jul 2019, In : Trends in Molecular Medicine. 25, 7, p. 626-639 14 p.

Research output: Contribution to journalReview article

2018

The wide utility of rabbits as models of human diseases

Esteves, P. J., Abrantes, J., Baldauf, H. M., BenMohamed, L., Chen, Y., Christensen, N., González-Gallego, J., Giacani, L., Hu, J., Kaplan, G., Keppler, O. T., Knight, K. L., Kong, X. P., Lanning, D. K., Le Pendu, J., De Matos, A. L., Liu, J., Liu, S., Lopes, A. M., Lu, S. & 17 others, Lukehart, S., Manabe, Y. C., Neves, F., McFadden, D., Pan, R., Peng, X., de Sousa-Pereira, P., Pinheiro, A., Rahman, M., Ruvoën-Clouet, N., Subbian, S., Tuñón, M. J., van der Loo, W., Vaine, M., Via, L. E., Wang, S. & Mage, R., May 2018, In : Experimental and Molecular Medicine. 50, 5, 66.

Research output: Contribution to journalArticle

22 Scopus citations

Oncolytic Virus-Mediated RAS Targeting in Rhabdomyosarcoma

Phelps, M. P., Yang, H., Patel, S., Rahman, M., McFadden, D. & Chen, E., Dec 21 2018, In : Molecular Therapy - Oncolytics. 11, p. 52-61 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2019

Parallel adaptation of rabbit populations to myxoma virus

Alves, J. M., Carneiro, M., Cheng, J. Y., de Matos, A. L., Rahman, M., Loog, L., Campos, P. F., Wales, N., Eriksson, A., Manica, A., Strive, T., Graham, S. C., Afonso, S., Bell, D. J., Belmont, L., Day, J. P., Fuller, S. J., Marchandeau, S., Palmer, W. J., Queney, G. & 9 others, Surridge, A. K., Vieira, F. G., McFadden, D., Nielsen, R., Thomas, M., Gilbert, P., Esteves, P. J., Ferrand, N. & Jiggins, F. M., Mar 22 2019, In : Science. 363, 6433, p. 1319-1326 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2020

Oncolytic Viruses and the Immune System: The Dynamic Duo

Lemos de Matos, A., Franco, L. S. & McFadden, G., Jun 12 2020, In : Molecular Therapy - Methods and Clinical Development. 17, p. 349-358 10 p.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

Ex Vivo Virotherapy with Myxoma Virus to Treat Cancer

Villa, N. Y., Franco, L. S. & McFadden, G., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 95-110 16 p. (Methods in Molecular Biology; vol. 2058).

Research output: Chapter in Book/Report/Conference proceedingChapter

Synergistic Combination of Oncolytic Virotherapy and Immunotherapy for Glioma

Tang, B., Guo, Z. S., Bartlett, D. L., Yan, D. Z., Schane, C. P., Thomas, D. L., Liu, J., McFadden, G., Shisler, J. L., Roy, E. J. & Roy, E. J., May 1 2020, In : Clinical Cancer Research. 26, 9, p. 2216-2230 15 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Quantifying Antigen-Specific T Cell Responses When Using Antigen-Agnostic Immunotherapies

van Vloten, J. P., Santry, L. A., McAusland, T. M., Karimi, K., McFadden, D., Petrik, J. J., Wootton, S. K. & Bridle, B. W., Jun 14 2019, In : Molecular Therapy - Methods and Clinical Development. 13, p. 154-166 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

White paper on microbial anti-cancer therapy and prevention

Forbes, N. S., Coffin, R. S., Deng, L., Evgin, L., Fiering, S., Giacalone, M., Gravekamp, C., Gulley, J. L., Gunn, H., Hoffman, R. M., Kaur, B., Liu, K., Lyerly, H. K., Marciscano, A. E., Moradian, E., Ruppel, S., Saltzman, D. A., Tattersall, P. J., Thorne, S., Vile, R. G. & 3 others, Zhang, H. H., Zhou, S. & McFadden, D., Aug 6 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 78.

Research output: Contribution to journalArticle

16 Scopus citations
2016
23 Scopus citations
2018

Crystal Structure of Cleaved Serp-1, a Myxomavirus-Derived Immune Modulating Serpin: Structural Design of Serpin Reactive Center Loop Peptides with Improved Therapeutic Function

Mahon, B. P., Ambadapadi, S., Yaron, J. R., Lomelino, C. L., Pinard, M. A., Keinan, S., Kurnikov, I., Macaulay, C., Zhang, L., Reeves, W., McFadden, D., Tibbetts, S., McKenna, R. & Lucas, A. R., Feb 20 2018, In : Biochemistry. 57, 7, p. 1096-1107 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2020

Mesenchymal stem cells as carriers for systemic delivery of oncolytic viruses

Hadryś, A., Sochanik, A., McFadden, G. & Jazowiecka-Rakus, J., May 5 2020, In : European Journal of Pharmacology. 874, 172991.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Autologous Transplantation Using Donor Leukocytes Loaded Ex Vivo with Oncolytic Myxoma Virus Can Eliminate Residual Multiple Myeloma

Villa, N. Y., Rahman, M. M., Mamola, J., D'Isabella, J., Goras, E., Kilbourne, J., Lowe, K., Daggett-Vondras, J., Torres, L., Christie, J., Appel, N., Cox, A. L., Kim, J. B. & McFadden, G., Sep 25 2020, In : Molecular Therapy - Oncolytics. 18, p. 171-188 18 p.

Research output: Contribution to journalArticle

Open Access
2017

Identification of host DEAD-box RNA helicases that regulate cellular tropism of oncolytic Myxoma virus in human cancer cells

Rahman, M., Bagdassarian, E., Ali, M. A. M. & McFadden, D., Dec 1 2017, In : Scientific reports. 7, 1, 15710.

Research output: Contribution to journalArticle

8 Scopus citations
4 Scopus citations