5-Propynyluracil·diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA

John C. Chaput; Surajit Sinha; Christopher Switzer

doi:10.1039/b204535d

5-Propynyluracil·diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA

John C. Chaput, Surajit Sinha, Christopher Switzer

CLAS-NS: Molecular Sciences, School of (SMS)

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The Up·D base-pair (5-propynyl uracil·diaminopurine) is found to be more effective at non-enzymatic transcription than the corresponding natural T·A pair; under non-enzymatic reaction conditions where the natural T·A base-pair fails, a DNA template bearing Up efficiently directs the incorporation of D into a product RNA strand.

Original language	English (US)
Pages (from-to)	1568-1569
Number of pages	2
Journal	Chemical Communications
Volume	2
Issue number	15
DOIs	https://doi.org/10.1039/b204535d
State	Published - Jan 1 2002

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/b204535d

Cite this

@article{8cdfd630a189498c84ec48d372c4d965,

title = "5-Propynyluracil·diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA",

abstract = "The Up·D base-pair (5-propynyl uracil·diaminopurine) is found to be more effective at non-enzymatic transcription than the corresponding natural T·A pair; under non-enzymatic reaction conditions where the natural T·A base-pair fails, a DNA template bearing Up efficiently directs the incorporation of D into a product RNA strand.",

author = "Chaput, {John C.} and Surajit Sinha and Christopher Switzer",

year = "2002",

month = jan,

day = "1",

doi = "10.1039/b204535d",

language = "English (US)",

volume = "2",

pages = "1568--1569",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "15",

}

TY - JOUR

T1 - 5-Propynyluracil·diaminopurine

T2 - an efficient base-pair for non-enzymatic transcription of DNA

AU - Chaput, John C.

AU - Sinha, Surajit

AU - Switzer, Christopher

PY - 2002/1/1

Y1 - 2002/1/1

N2 - The Up·D base-pair (5-propynyl uracil·diaminopurine) is found to be more effective at non-enzymatic transcription than the corresponding natural T·A pair; under non-enzymatic reaction conditions where the natural T·A base-pair fails, a DNA template bearing Up efficiently directs the incorporation of D into a product RNA strand.

AB - The Up·D base-pair (5-propynyl uracil·diaminopurine) is found to be more effective at non-enzymatic transcription than the corresponding natural T·A pair; under non-enzymatic reaction conditions where the natural T·A base-pair fails, a DNA template bearing Up efficiently directs the incorporation of D into a product RNA strand.

UR - http://www.scopus.com/inward/record.url?scp=0036073483&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036073483&partnerID=8YFLogxK

U2 - 10.1039/b204535d

DO - 10.1039/b204535d

M3 - Article

AN - SCOPUS:0036073483

VL - 2

SP - 1568

EP - 1569

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 15

ER -

5-Propynyluracil·diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this