3 Scopus citations

Abstract

Small structure segmentation from medical images is a challenging problem yet has important applications. Examples are labeling cell, lesion and glomeruli for disease diagnosis, just to name a few. Though extensive research has proposed various detectors for this type of problem, most are 2D detectors. Recently, we have developed a Hessian based 3D detector to segment small structures from medical images (e.g., MRI). In our detector, two 3D geometrical features: regional blobness and flatness, in conjunction with the intensity features are fully utilized to serve the segmentation purpose. The objective of this research is to further improve the 3D detector with additions of texture features. Medical images contain rich information which can be presented as texture, the local characteristics pattern of image intensity. We hypothesize the Hessian based detector extended with the 3D texture features is expected to have improved performance in segmenting small structures. To thoroughly evaluate the contributions from the textual features, 25 synthetic images and 6 real world rat MR images are studied. It is observed the combination of intensity, blobness, and two texture features: intensity standard deviation and entropy improves performance in synthetic dataset by about 19% in F-score, and performs as well as other detectors on rat MR images.

Original languageEnglish (US)
Title of host publication2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages6433-6436
Number of pages4
Volume2016-October
ISBN (Electronic)9781457702204
DOIs
StatePublished - Oct 13 2016
Event38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States
Duration: Aug 16 2016Aug 20 2016

Other

Other38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
CountryUnited States
CityOrlando
Period8/16/168/20/16

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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