3D Printed Microfluidic Actuation System for Multi-step Paper-based Assays

Sumeyra Agambayev, Mark Bailly, Jennifer Blain Christen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a novel 3D printed Microfluidic Actuation System for lateral flow assay in low resource settings. The system is used to deliver reagents for multi-step assays from blisters placed into cavities in the 3D printed assembly. The system is operated by manually depressing the blister housing and rotating to the next blister location. This is repeated for each step in the assay to enable a simple and repeatable method of delivering specified volumes to the assay at arbitrary time intervals as required by the assay. The blisters provide for robust storage while maintaining consistent aliquots for the assay. We characterize the percent of the total volume delivered to the lateral flow assay from the blisters including the volume dispensed at given time intervals.

Original languageEnglish (US)
Title of host publication2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages155-158
Number of pages4
ISBN (Electronic)9781728138121
DOIs
StatePublished - Nov 2019
Event2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019 - Bethesda, United States
Duration: Nov 20 2019Nov 22 2019

Publication series

Name2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019

Conference

Conference2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019
CountryUnited States
CityBethesda
Period11/20/1911/22/19

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ASJC Scopus subject areas

  • Artificial Intelligence
  • Computer Science Applications
  • Biomedical Engineering
  • Health Informatics
  • Instrumentation
  • Health(social science)

Cite this

Agambayev, S., Bailly, M., & Christen, J. B. (2019). 3D Printed Microfluidic Actuation System for Multi-step Paper-based Assays. In 2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019 (pp. 155-158). [8962668] (2019 IEEE Healthcare Innovations and Point of Care Technologies, HI-POCT 2019). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/HI-POCT45284.2019.8962668