TY - JOUR
T1 - 3D-Printable Biodegradable Polyester Tissue Scaffolds for Cell Adhesion
AU - Sirrine, Justin M.
AU - Pekkanen, Allison M.
AU - Nelson, Ashley M.
AU - Chartrain, Nicholas A.
AU - Williams, Christopher B.
AU - Long, Timothy E.
N1 - Funding Information:
This material is based on work supported in part by the Howard Hughes Medical Institute through the Scieneering Program. We acknowledge the Institute for Critical Technology and Applied Science (ICTAS) and the Design, Research, and Education for Additive Manufacturing Systems (DREAMS) laboratories at Virginia Tech for instrumental support.
Publisher Copyright:
© 2015 Journal compilation CSIRO.
PY - 2015
Y1 - 2015
N2 - Additive manufacturing, or three-dimensional (3D) printing, has emerged as a viable technique for the production of vascularized tissue engineering scaffolds. In this report, a biocompatible and biodegradable poly(tri(ethylene glycol) adipate) dimethacrylate was synthesized and characterized for suitability in soft-tissue scaffolding applications. The polyester dimethacrylate exhibited highly efficient photocuring, hydrolyzability, and 3D printability in a custom microstereolithography system. The photocured polyester film demonstrated significantly improved cell attachment and viability as compared with controls. These results indicate promise of novel, printable polyesters for 3D patterned, vascularized soft-tissue engineering scaffolds.
AB - Additive manufacturing, or three-dimensional (3D) printing, has emerged as a viable technique for the production of vascularized tissue engineering scaffolds. In this report, a biocompatible and biodegradable poly(tri(ethylene glycol) adipate) dimethacrylate was synthesized and characterized for suitability in soft-tissue scaffolding applications. The polyester dimethacrylate exhibited highly efficient photocuring, hydrolyzability, and 3D printability in a custom microstereolithography system. The photocured polyester film demonstrated significantly improved cell attachment and viability as compared with controls. These results indicate promise of novel, printable polyesters for 3D patterned, vascularized soft-tissue engineering scaffolds.
UR - http://www.scopus.com/inward/record.url?scp=84941070913&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84941070913&partnerID=8YFLogxK
U2 - 10.1071/CH15327
DO - 10.1071/CH15327
M3 - Article
AN - SCOPUS:84941070913
SN - 0004-9425
VL - 68
SP - 1409
EP - 1414
JO - Australian Journal of Chemistry
JF - Australian Journal of Chemistry
IS - 9
ER -