Abstract
(2S,3S,4R)-4-Amino-3-hydroxy-2-methylvalerate, an amino acid constituent of the antitumor antibiotic bleomycin, has been prepared from L-rhamnose. This approach to a chiral 3-hydroxy-2-methylcarboxylate constitutes an alternative to the stereoselective aldol condensation.
Original language | English (US) |
---|---|
Pages (from-to) | 1232-1234 |
Number of pages | 3 |
Journal | Journal of Organic Chemistry |
Volume | 46 |
Issue number | 6 |
DOIs | |
State | Published - Mar 1981 |
Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry