Unraveling the second secret of life: Are all proteins allosteric (ASUF 30007808)

Project: Research project

Project Details

Description

Unraveling the second secret of life: Are all proteins allosteric (ASUF 30007808) Unravelling the second secret of life: are all proteins allosteric Monod considered his contribution on allostery to be even more significant than the operon model, claiming that he had discovered the second secret of life [1]. However, after almost five decades of intense research, we still do not yet understand the mechanism by which distant protein residues communicate, or how prevalent this phenomenon is. Here, we will combine recently-developed theoretical and experimental methods from the Ozkan and Fordyce labs to answer the question: how well can we create allostery?
StatusFinished
Effective start/end date9/13/178/30/19

Funding

  • Gordon and Betty Moore Foundation: $56,250.00

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