Mechanisms of 5HT2AR regulation by Egr3 - Xiul Zhao Mechanisms of 5HT2AR regulation by Egr3 - Xiul Zhao Arizona State University - Statement of Work Xiuli Zhao ASU Ph.D. Candidate in the Interdisciplinary Graduate Program in Neuroscience. Xiuli Zhao will be working with Amelia Gallitano, MD, PhD, Associate Professor of Basic Medical Sciences, College of Medicine, Phoenix to conduct research studies that include animal behavior, surgical, histological, and pharmacology studies, and molecular biology experiments. Her work will also involve literature searches, computer and statistical analyses, presentations of data, and writing of scientific papers. She will be working on Specific Aim 2 of the project. She will work with Dr. Gallitano comparing Htr2a expression in WT and Egr3-/- mice at baseline and following exposure to stressors that induce Egr3 expression in WT mice, using quantitative real-time (QRT) PCR and ISHH. She will perform chromatin immunoprecipitation followed by QRT-PCR using an anti-EGR3 Ab to demonstrate binding of EGR3 to the Htr2a promoter in the PFC.
|Effective start/end date||7/1/13 → 12/31/16|
- HHS-NIH: National Institute of Mental Health (NIMH): $134,329.00
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