We aim to develop self-assembling DNA nanoscaffolds to organize nanoparticles (NPs) into rationally designed, spatially addressable architectures for nanoelectronics/photonics applications. Metallic and semiconducting nanoparticles (QDs) are being actively developed as electronic device building blocks. When such materials are organized into well-defined ensembles, their collective properties depend critically on inter-particle spacing and hierarchical organization. Building on top of our recent success (e.g. Seemans DNA templated gold NP arrays and Yans DNA templated goldY1 and QDY2 arrays) in DNA tile directed self-assembly, we aim to design hierarchical self-assembly strategies to organize spatially addressable discrete NP nanostructures into more complex architectures. In brief, the DNA nanostructures serve as both templating elements and interconnect glues. Such goals can only be achieved through synergistic efforts between our team members. For example, Seemans group has demonstrated stepwise self-assembly of DNA Origami tiles into higher order discrete super-structures (Seeman, unpublished data). Yans group has developed various approaches for more robust bioconjugation of DNA to both gold NPsY3 and QDsY4. The discrete NP nanoarchitectures will be further assembled and orientated onto solid substrates through the molecular lithographic approach developed by Maos group and the nanoimprinting technology pioneered by Chous group. Indeed, our previous work has demonstrated that it is possible to use lithographic approach to align DNA nanotube structures into miroscale networks.
|Effective start/end date||11/1/08 → 11/1/11|
- DOD-NAVY: Office of Naval Research (ONR): $226,500.00