Limiting resource ratio theory (also called ecological stoichiometry (ES)) and evolution have been found to be crucial lens through which one can view and understand the dynamics of populations and communities of microorganisms. ES covers multiple biological scales, and it allows the construction of robust, mechanistic, and predictive mathematical models based on cell nutrient quotas. Within this theory, the utilization of energy and multiple chemical elements (especially carbon, nitrogen, and phosphorus) between organisms and their environment occupies a central position. However, ES framework has yet to be effectively integrated into the modeling of host-pathogen interactions. Our goal is to identify the relationship of some key biological mechanisms to the rich dynamics often observed in simulating population models incorporating nutrient quality and quantity.
|Effective start/end date||9/1/16 → 8/31/20|
- National Science Foundation (NSF): $193,873.00