This is a request for an REU supplement to the PIs CAREER AWARD project Molecular Evolution of Telomerase Ribonucleoprotein: A Phylogenetic Study of Telomerase RNA Structure and Function (06/15/2007 06/14/2012). To integrate research and undergraduate education, this proposed work for the REU supplement will include two objectives: (1) To update and improve the web-based "Telomerase Database" that we established in 2007; (2) to give undergraduate students interdisciplinary training in bioinformatics and molecular biology. Two talented undergraduate students, Ryan Niedzielko and Anthony Young, have been recruited to carry out this project for the summer of 2009. They are selected because of their outstanding academic performance. Ryan Niedzielko has a GPA of 3.92 and Anthony Young has a GPA of 3.41. Ryan and Anthony will work together to complete the proposed project. They will search and read literatures to identify new telomerase-related protein and RNA genes. They will learn how to use advanced bioinformatic programs to search for unknown telomerase protein or RNA genes from genome databases. They will each work on cloning of a TERT protein gene from different species. This will help them learn how to use techniques in molecular biology in real-life research settings.
|Effective start/end date||6/15/07 → 5/31/13|
- NSF: Directorate for Biological Sciences (BIO): $698,155.00
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