An exploratory analysis of Ca isotope ratios in urine samples of prostate cancer patients

Project: Research project

Project Details

Description

An exploratory analysis of Ca isotope ratios in urine samples of prostate cancer patients An exploratory analysis of Ca isotope ratios in urine samples of prostate cancer patients Abstract The purpose of this study is to try and validate a real time measure of bone turnover to help monitor the progression of prostate cancer and androgen deprivation induced bone disease to an individualized basis for initiation of bone strengthening agents. Our objective is to include prospective collection of serial urine calcium isotope measurements within prostate cancer treatment trials at Mayo Clinic to establish the utility of Ca isotope ration changes as a tool to guide treatment. CA ratios may have clinically beneficial applications since bone densitometry and currently used biomarkers are insufficient to detect and quantify bone loss until it has occurred. To date, collaborators at and Arizona State University have explored calcium isotope ratios in multiple myeloma patients with results consistent with expectations.
StatusFinished
Effective start/end date4/1/133/18/14

Funding

  • Mayo Clinic Arizona: $5,560.00

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